Evidence map›Paper›PMID 27595130›Full record

ArticleData in brief2016

Data supporting the high-accuracy haplotype imputation using unphased genotype data as the references.

Wenzhi Li, Wei Xu, Shaohua He, Li Ma, Qing Song

Abstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenzhi LiCenter of Big Data and Bioinformatics, First Affiliated Hospital of Medicine School, Xi'an Jiaotong University, Xi'an, Shaanxi, China; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA.
Wei XuCardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA.
Shaohua He4DGenome Inc., Atlanta, GA, USA.
Li MaCardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA; 4DGenome Inc., Atlanta, GA, USA.
Qing SongCenter of Big Data and Bioinformatics, First Affiliated Hospital of Medicine School, Xi'an Jiaotong University, Xi'an, Shaanxi, China; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, GA, USA; 4DGenome Inc., Atlanta, GA, USA.

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI ZHAO, XUEYING · 1986 to 2011
$32.4M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MAYBERRY, ROBERT M · 2012 to 2018
$24.8M
TRANSPLANTATION OF EXOSOMES FROM HYPOXIA-PRECONDITIONED ADIPOSE-DERIVED STEM CELLS PROMOTES ANGIOGENESIS IN ISCHEMIC HEARTG12MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI BOND, VINCENT C · 2012 to 2017
$18.4M
Minority Health-GRID Network: A Genomics Resource for Health Disparity ResearchRC4MD005964 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIS, ROBERT LOWELL, NICKERSON, DEBORAH A · 2010 to 2010
$13.3M
Morehouse Cardiovascular Research Center of ExcellenceP50HL117929 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI TAYLOR, HERMAN ALFRED · 2013 to 2018
$6.7M
Determining the Phased Genome SequencesR21HG006173 · NHGRI · MOREHOUSE SCHOOL OF MEDICINE · PI SONG, QING · 2012 to 2013
$389k
Cost-effective and high-throughput chromosomal haplotypingR43HG007621 · NHGRI · 4DGENOME, INC. · PI SONG, QING · 2014 to 2014
$219k
NCRR NIH HHS G12 RR003034NHGRI NIH HHS R21 HG006173NHGRI NIH HHS R43 HG007621NHLBI NIH HHS P50 HL117929NIMHD NIH HHS G12 MD007602NIMHD NIH HHS RC4 MD005964NIMHD NIH HHS S21 MD000101NIMHD NIH HHS U54 MD007588
6 · The paper itself

Abstract

The data presented in this article is related to the research article entitled "High-accuracy haplotype imputation using unphased genotype data as the references" which reports the unphased genotype data can be used as reference for haplotyping imputation [1]. This article reports different implementation generation pipeline, the results of performance comparison between different implementations (A, B, and C) and between HiFi and three major imputation software tools. Our data showed that the performances of these three implementations are similar on accuracy, in which the accuracy of implementation-B is slightly but consistently higher than A and C. HiFi performed better on haplotype imputation accuracy and three other software performed slightly better on genotype imputation accuracy. These data may provide a strategy for choosing optimal phasing pipeline and software for different studies.

Identifiers

PMID27595130
PMCPMC4995474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.