ReviewKnee surgery & related research2016
Blood Management Strategies in Total Knee Arthroplasty.
Review in Knee surgery & related research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- A comparison of efficacy and safety of oral versus intravenous applications of tranexamic acid in total hip and knee arthroplasty: an updated systematic review meta-analysis of randomized controlled trials.BMC musculoskeletal disorders · 2025Pooled it
- Comparison of clinical outcomes of VISIONAIRE patient-specific instrumentation with conventional instrumentation in total knee arthroplasty: a systematic literature review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Should synovectomy be performed in primary total knee arthroplasty for osteoarthritis? A meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2019Pooled it
- Is combined use of intravenous and intraarticular tranexamic acid superior to intravenous or intraarticular tranexamic acid alone in total knee arthroplasty? A meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2017Pooled it
- Efficacy and Safety of Bone Wax Application at Different Time Points to Reduce Postoperative Blood Loss in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.Orthopaedic surgery · 2024Trial
- Reduction of Blood Loss by Intra-articular Injection of Tranexamic Acid Combined with Knee and Hip Flexion at 45° During Primary Total Knee Arthroplasty: A Randomized Controlled Trial.Orthopaedic surgery · 2020Trial
- Effect of forced-air warming system in prevention of postoperative hypothermia in elderly patients: A Prospective controlled trial.Medicine · 2019Trial
- Association of oxidized regenerated cellulose powder and tranexamic acid during total knee arthroplasty: clinical outcomes.International orthopaedics · 2026Article
- Interpretable Machine Learning Analysis of Factors Associated with Postoperative Hemoglobin Reduction After Total Knee Arthroplasty: A Standardized-Protocol Cohort Study in Non-Transfused Patients.Journal of clinical medicine · 2026Article
- Tranexamic acid in high-risk shoulder arthroplasty patients: safety across thromboembolic, cardiac, renal, and neurologic risk profiles.Archives of orthopaedic and trauma surgery · 2026Article
- Implementation of an institutional Enhanced Recovery After Surgery (ERAS) pathway is associated with fewer in-hospital falls after total knee arthroplasty.Journal of experimental orthopaedics · 2026Article
- A prospective cohort study develops and validates a machine learning model for predicting ecchymosis after total knee arthroplasty.Scientific reports · 2026Article
- Article
- Personalized bleeding management in total knee arthroplasty using reference change value: comparative analysis of tourniquet versus non-tourniquet techniques.Archives of orthopaedic and trauma surgery · 2025Article
- Balancing efficiency and patient safety: lessons from the trend to outpatient lower joint arthroplasty.Anaesthesia · 2025Article
- A prospective randomized placebo-controlled study evaluating the safety and benefits of tranexamic acid injections for primary unilateral total knee replacement.Journal of orthopaedic case reports · 2025Article
- Timing and risk factors of complications following total knee arthroplasty.Annals of medicine and surgery (2012) · 2024Article
- Routine Postoperative Hemoglobin and Hematocrit Tests Are Unnecessary Following Primary Total Hip and Knee Arthroplasty.Arthroplasty today · 2024Article
- A Decline in Overutilization of Transfusion after Total Knee Arthroplasty Using Pharmacological Agents for Patient Blood Management in South Korea: An Analysis Based on the Korean National Health Insurance Claims Database from 2008 to 2019.Clinics in orthopedic surgery · 2023Article
- Effects of Thrombin-Based Hemostatic Agent in Total Knee Arthroplasty: Meta-Analysis.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A perioperative blood management program is one of a number of important elements for successful patient care in total knee arthroplasty (TKA) and surgeons should be proactive in its application. The aims of blood conservation are to reduce the risk of blood transfusion whilst at the same time maximizing hemoglobin (Hb) in the postoperative period, leading to a positive effect on outcome and cost. An individualized strategy based on patient specific risk factors, anticipated blood loss and comorbidities are useful in achieving this aim. Multiple blood conservation strategies are available in the preoperative, intraoperative and postoperative periods and can be employed in various combinations. Recent literature has highlighted the importance of preoperative Hb optimization, minimizing blood loss and evidence-based transfusion guidelines. Given TKA is an elective procedure, a zero allogenic blood transfusion rate should be the aim and an achievable goal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.