Evidence map›Paper›PMID 27595036›Full record

ArticleVeterinary medicine international2016

Bayesian Estimation of Sensitivity and Specificity of Rose Bengal, Complement Fixation, and Indirect ELISA Tests for the Diagnosis of Bovine Brucellosis in Ethiopia.

T Getachew, G Getachew, G Sintayehu, M Getenet, A Fasil

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Seroprevalence ofFrontiers in veterinary science · 2024
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  9. Seroprevalence ofMicroorganisms · 2023
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  10. Review
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  12. Article
  13. Article
  14. Article
  15. Bovine brucellosis - a comprehensive review.The veterinary quarterly · 2021
    Review
  16. Seroprevalence ofVeterinary world · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

T GetachewNational Animal Health Diagnostic and Investigation Center (NAHDIC), Ethiopian Ministry of Livestock and Fisheries Development, P.O. Box 04, Sebeta, Ethiopia.
G GetachewNational Animal Health Diagnostic and Investigation Center (NAHDIC), Ethiopian Ministry of Livestock and Fisheries Development, P.O. Box 04, Sebeta, Ethiopia.
G SintayehuNational Animal Health Diagnostic and Investigation Center (NAHDIC), Ethiopian Ministry of Livestock and Fisheries Development, P.O. Box 04, Sebeta, Ethiopia.ORCID 0000-0002-8403-5694
M GetenetNational Animal Health Diagnostic and Investigation Center (NAHDIC), Ethiopian Ministry of Livestock and Fisheries Development, P.O. Box 04, Sebeta, Ethiopia.
A FasilNational Animal Health Diagnostic and Investigation Center (NAHDIC), Ethiopian Ministry of Livestock and Fisheries Development, P.O. Box 04, Sebeta, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Test evaluation in the absence of a gold standard test was conducted for the diagnosis and screening of bovine brucellosis using three commercially available tests including RBPT, CFT, and I-ELISA in National Animal Health Diagnostic and Investigation Center (NAHDIC) Ethiopia. A total of 278 sera samples from five dairy herds were collected and tested. Each serum sample was subjected to the three tests and the results obtained were recorded and the test outcomes were cross-classified to estimate the sensitivity and specificity of the tests using Bayesian model. Prior information generated on the sensitivity and specificity of bovine brucellosis from published data was used in the model. The three test-one population Bayesian model was modified and applied using WinBug software with the assumption that the dairy herds have similar management system and unknown disease status. The Bayesian posterior estimate for sensitivity was 89.6 (95% PI: 79.9-95.8), 96.8 (95% PI: 92.3-99.1), and 94 (95% PI: 87.8-97.5) and for specificity was 84.5 (95% PI: 68-94.98), 96.3 (95% PI: 91.7-98.8), and 88.5 (95% PI: 81-93.8) for RBT, I-ELISA, and CFT, respectively. In this study I-ELISA was found with the best sensitivity and specificity estimates 96.8 (95% PI: 92.3-99.1) and 96.3 (95% PI: 91.7-98.8), compared to both CFT and RBPT.

Identifiers

PMID27595036
PMCPMC4993953
OpenAlexW2516492025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.