Evidence map›Paper›PMID 27595020›Full record

ArticleTuberculosis research and treatment2016

Impact of WHO 2010 Guidelines on Antiretroviral Therapy Initiation among Patients with HIV-Associated Tuberculosis in Clinics with and without Onsite HIV Services in the Democratic Republic of Congo.

Marcel Yotebieng, Martine Tabala, Marie Louise Batumbula, Landry Wenzi, Emmanuel Basaki, Eugenie Mungoyo, Richard Mangala, Frieda Behets

Abstract read
In one paragraph

Article in Tuberculosis research and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcel YotebiengDivision of Epidemiology, College of Public Health, The Ohio State University, 304 Cunz Hall, 1841 Neil Avenue, Columbus, OH 43210-1351, USA; Department of Epidemiology, The University of North Carolina at Chapel Hill, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB No. 7435, Chapel Hill, NC 27599-7435, USA.ORCID 0000-0003-2110-2631
Martine TabalaSchool of Public Health, The University of Kinshasa, Kinshasa, Congo.
Marie Louise BatumbulaDepartment of Epidemiology, The University of North Carolina at Chapel Hill, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB No. 7435, Chapel Hill, NC 27599-7435, USA; School of Public Health, The University of Kinshasa, Kinshasa, Congo.
Landry WenziSchool of Public Health, The University of Kinshasa, Kinshasa, Congo.
Emmanuel BasakiSchool of Public Health, The University of Kinshasa, Kinshasa, Congo.
Eugenie MungoyoSchool of Public Health, The University of Kinshasa, Kinshasa, Congo.
Richard MangalaSchool of Public Health, The University of Kinshasa, Kinshasa, Congo.
Frieda BehetsDepartment of Epidemiology, The University of North Carolina at Chapel Hill, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB No. 7435, Chapel Hill, NC 27599-7435, USA; School of Medicine, The University of North Carolina at Chapel Hill, 333 South Columbia Street, MacNider Hall, Room No. 348, CB No. 7240, Chapel Hill, NC 27599-7240, USA.

Funding

"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
PACT-PROVIDING AIDS CARE & TREATMENT IN THE DEMOCRATICS REPUBLIC OF CONGO UNDER U2GPS001179 · PS · UNIVERSITY OF NORTH CAROLINA SYSTEM · PI BEHETS, WILFRIDA M · 2008 to 2013
$12.7M
Conditional cash transfers to increase uptake of and retention of PMTCT servicesR01HD075171 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOTEBIENG, MARCEL · 2012 to 2013
$778k
NCHHSTP CDC HHS U2G PS001179NIAID NIH HHS U01 AI096299NICHD NIH HHS R01 HD075171
6 · The paper itself

Abstract

Background. We assessed the impact of WHO's 2010 guidelines that removed the requirement of CD4 count before ART, on timely initiation of ART among HIV/TB patients in the Democratic Republic of Congo (DRC). Methods. Data collected to monitor implementation of provider initiated HIV testing and counseling (PITC) and linkage to HIV care from 65 and 13 TB clinics in Kinshasa and Kisangani, respectively, between November 2010 and June 2013. Results. Prior to the WHO's 2010 guidelines, in Kinshasa, 79.1% (401/507) of HIV/TB patients referred for HIV services were initiated on ART in clinics with onsite ART services compared to 50.0% (63/123) in clinics without. Following the implementation of the new guidelines, 89.8% (714/795) and 93.0% (345/371) of HIV/TB patients referred for HIV services were initiated on ART, respectively, in clinics with onsite and without onsite ART services. Similarly, in Kisangani, 69.7% (53/120) and 36.4% (16/44) in clinics with and without onsite ART service, respectively, were initiated on ART prior to the 2010 guidelines and 88.8% (135/152) and 72.6% (106/146), respectively, after the new guidelines. Conclusion. Though implementation of the 2010 guidelines increased the proportion of HIV/TB patients initiated on ART substantially, it remained below the 100% target, particularly in clinics without onsite ART services.

Identifiers

PMID27595020
PMCPMC4993947

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.