Evidence map›Paper›PMID 27594809›Full record

ArticleAddictive disorders & their treatment2016

Differential Impact of Depressive and Manic Mood States on Alcohol Craving in Comorbid Bipolar Alcoholism: Preliminary Findings.

Dalia N Balsamo, Antoine Douaihy, Jack R Cornelius, Dennis C Daley, Levent Kirisci, Scott M Hyman, Ihsan M Salloum

Abstract read
In one paragraph

Article in Addictive disorders & their treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dalia N BalsamoChild Study Center, Yale University School of Medicine.
Antoine DouaihyDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Jack R CorneliusDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Dennis C DaleyDepartment of Psychiatry, University of Pittsburgh School of Medicine.
Levent KirisciSchool of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy.
Scott M HymanDepartment of Psychiatry, University of Miami-Miller School of Medicine; Carlos Albizu University, Doctoral Program in Clinical Psychology.
Ihsan M SalloumDepartment of Psychiatry, University of Miami-Miller School of Medicine.
University of Pittsburgh · USCarlos Albizu University · PRUniversity of Miami · USYale University · US

Funding

Optimizing Pharmacotherapy for Bipolar AlcoholicsR01AA015385 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SALLOUM, IHSAN M · 2006 to 2010
$2.4M
COMBINED PHARMACOTHERAPY IN DEPRESSED ALCOHOLICSR01AA011929 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SALLOUM, IHSAN M · 2000 to 2004
$1.9M
NIAAA NIH HHS R01 AA011929NIAAA NIH HHS R01 AA015385
6 · The paper itself

Abstract

objectivesTo examine the differential impact of depressive and manic mood states on alcohol craving in patients with bipolar disorder and comorbid alcoholism.

methodsForty-four men and women, ages 18-65, with DSM-IV-TR comorbid diagnoses of bipolar I disorder and alcohol dependence were assessed over a three-month period to examine the extent to which their depressive and manic symptoms were associated with alcohol cravings (i.e., desire to use and not to use alcohol) at each assessment point, controlling for age, ethnicity, socio-economic status, baseline alcohol use, and number of assessments.

resultsBoth manic and depressive symptoms were associated with greater desire to use alcohol. Only depressive symptomatology was associated with reduced desire

conclusionWhereas enhanced desire to drink alcohol may be a conditioned reaction to both manic and depressed mood states, desire not to drink alcohol may be more of an indicator of treatment motivation, which is negatively affected by depressed mood. Depressive symptoms may warrant prioritization and aggressive targeting early in treatment given that desire to refrain from alcohol use was only influenced by depressive symptoms and declined over the course of treatment.

Indexed as

alcohol use disorderbipolar disordercravingdepressionmania

Identifiers

PMID27594809
PMCPMC5004758
OpenAlexW2418022115

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.