Evidence map›Paper›PMID 2759422›Full record

ArticleGenetics1989

Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.

L D Siracusa, A M Buchberg, N G Copeland, N A Jenkins

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
  2. A large-sample QTL study in mice: III. Reproduction.Mammalian genome : official journal of the International Mammalian Genome Society · 2004
    Article
  3. Eyes absent: a gene family found in several metazoan phyla.Mammalian genome : official journal of the International Mammalian Genome Society · 1997
    Article
  4. The Cdc25 genes map to mouse chromosomes 2, 9, and 18.Mammalian genome : official journal of the International Mammalian Genome Society · 1996
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Low resolution mapping around the flavivirus resistance locus (Flv) on mouse chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  10. Article
  11. A high-resolution linkage map of the lethal spotting locus: a mouse model for Hirschsprung disease.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  12. Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  13. Article
  14. Article
  15. Genetic mapping of DNA topoisomerase I-related sequences to mouse chromosomes 2 and 14.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  16. Association of Xmv-10 and the non-agouti (a) mutation explained by close linkage instead of causality.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  17. Article
  18. Mouse chromosome 2.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  19. Mouse chromosome 14.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
  20. Localization of phospholipase C-gamma 1 to mouse chromosome 2.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L D SiracusaMammalian Genetics Laboratory, NCI-Frederick Cancer Research Facility, Maryland 21701.
A M Buchberg
N G Copeland
N A Jenkins
Cancer Research Center · US

Funding

PROVIDE BASIC CANCER RESEARCHN01CO074101 · CO · ADVANCED BIOSCIENCE LABORATORIES, INC. · PI VANDE WOUDE, GEORGE F · 1987 to 1994
–
NCI NIH HHS N01-CO-74101
6 · The paper itself

Abstract

Recombinant inbred strain and interspecific backcross mice were used to create a molecular genetic linkage map of the distal portion of mouse chromosome 2. The orientation and distance of the Ada, Emv-13, Emv-15, Hck-1, Il-1a, Pck-1, Psp, Src-1 and Svp-1 loci from the beta 2-microglobulin locus and the agouti locus were established. Our mapping results have provided the identification of molecular markers both proximal and distal to the agouti locus. The recombinants obtained provide valuable resources for determining the direction of chromosome walking experiments designed to clone sequences at the agouti locus. Comparisons between the mouse and human genome maps suggest that the human homolog of the agouti locus resides on human chromosome 20q. Three loci not present on mouse chromosome 2 were also identified and were provisionally named Psp-2, Hck-2 and Hck-3. The Psp-2 locus maps to mouse chromosome 14. The Hck-2 locus maps near the centromere of mouse chromosome 4 and may identify the Lyn locus. The Hck-3 locus maps near the distal end of mouse chromosome 4 and may identify the Lck locus.

Indexed as

AnimalsChromosome MappingCrosses, GeneticDNA ProbesGenetic MarkersHumansMiceMice, Inbred C57BLMuridaeMutationRecombination, GeneticSkin PigmentationSpecies SpecificityDNA ProbesGenetic Markers

Identifiers

PMID2759422
PMCPMC1203740
OpenAlexW2142799182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.