Evidence map›Paper›PMID 27594188›Full record

ReviewMayo Clinic proceedings2016

Antidepressant-Induced Female Sexual Dysfunction.

Tierney Lorenz, Jordan Rullo, Stephanie Faubion

Open access · greenAbstract readReview
In one paragraph

Review in Mayo Clinic proceedings, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 7 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 7 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
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  6. Pooled it
  7. Pooled it
  8. Trial
  9. Modern methods of treating vaginal dryness and atrophy.Przeglad menopauzalny = Menopause review · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Minimally Invasive Sacrocolpopexy: Impact on Sexual Function.International urogynecology journal · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tierney LorenzKinsey Institute and Center for the Integrative Study of Animal Behavior, Indiana University, Bloomington; Dr Lorenz is now with the Department of Psychology, University of North Carolina at Charlotte. Electronic address: tlorenz@uncc.edu.
Jordan RulloWomen's Health Clinic, Division of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
Stephanie FaubionWomen's Health Clinic, Division of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN.
Mayo Clinic · USUniversity of North Carolina at Charlotte · US

Funding

Common Themes in Reproductive DiversityT32HD049336 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI DALE R SENGELAUB · 2005 to 2026
$4.4M
NICHD NIH HHS T32 HD049336
6 · The paper itself

Abstract

Because 1 in 6 women in the United States takes antidepressants and a substantial proportion of patients report some disturbance of sexual function while taking these medications, it is a near certainty that the practicing clinician will need to know how to assess and manage antidepressant-related female sexual dysfunction. Adverse sexual effects can be complex because there are several potentially overlapping etiologies, including sexual dysfunction associated with the underlying mood disorder. As such, careful assessment of sexual function at the premedication visit followed by monitoring at subsequent visits is critical. Treatment of adverse sexual effects can be pharmacological (dose reduction, drug discontinuation or switching, augmentation, or using medications with lower adverse effect profiles), behavioral (exercising before sexual activity, scheduling sexual activity, vibratory stimulation, psychotherapy), complementary and integrative (acupuncture, nutraceuticals), or some combination of these modalities.

Indexed as

AdultAgedAged, 80 and overAntidepressive AgentsDepressive DisorderFemaleHumansMiddle AgedSelective Serotonin Reuptake InhibitorsSexual BehaviorSexual Dysfunction, PhysiologicalUnited StatesAntidepressive AgentsSelective Serotonin Reuptake Inhibitors

Identifiers

PMID27594188
PMCPMC6711470
OpenAlexW2511250611

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.