Evidence map›Paper›PMID 27594091›Full record

ArticleJournal of labelled compounds & radiopharmaceuticals2016

Synthesis and evaluation of an

Phoebe Y H Lam, Christopher R T Hillyar, Sarah Able, Katherine A Vallis

Open access · hybridAbstract read
In one paragraph

Article in Journal of labelled compounds & radiopharmaceuticals, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Advances in aptamer-based nuclear imaging.European journal of nuclear medicine and molecular imaging · 2022
    Review
  6. Review
  7. Review
  8. Synthesis and evaluation of anJournal of labelled compounds & radiopharmaceuticals · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Phoebe Y H LamDepartment of Oncology, CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, UK.
Christopher R T HillyarDepartment of Oncology, CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, UK.
Sarah AbleDepartment of Oncology, CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, UK.
Katherine A VallisDepartment of Oncology, CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, UK. katherine.vallis@oncology.ox.ac.uk.
CRUK/MRC Oxford Institute for Radiation Oncology · GBUniversity of Oxford · GB

Funding

Cancer Research UK 11564
6 · The paper itself

Abstract

The surface overexpression of nucleolin provides an anchor for the specific attachment of biomolecules to cancer and angiogenic endothelial cells. The peptide F3 is a high-affinity ligand of the nucleolin receptor (NR) that has been investigated as a carrier to deliver biologically active molecules to tumors for both therapeutic and imaging applications. A site-specific PEGylated F3 derivative was radiolabeled with [

Indexed as

Fluorine RadioisotopesGene Expression Regulation, NeoplasticAmino Acid SequenceBinding, CompetitiveBiological TransportCell Line, TumorChemistry Techniques, SyntheticDrug StabilityEndothelial CellsHumansHydrophobic and Hydrophilic InteractionsIndium RadioisotopesIsotope LabelingNucleolinPeptidesPhosphoproteinsFluorine RadioisotopesIndium RadioisotopesNucleolinPeptidesPhosphoproteinsRNA-Binding Proteins[18F]Al-Fendothelial cellsF3nucleolin receptortransglutaminase

Identifiers

PMID27594091
PMCPMC5082555
OpenAlexW2513006155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.