Evidence map›Paper›PMID 27592800›Full record

ArticleThe Journal of investigative dermatology2017

TIGIT and Helios Are Highly Expressed on CD4

Neha Jariwala, Bernice Benoit, Andrew V Kossenkov, Landon K Oetjen, Timothy M Whelan, Christine M Cornejo, Junko Takeshita, Brian S Kim, Louise C Showe, Maria Wysocka and 1 more

Open access · hybridAbstract readComparative StudyLetter
In one paragraph

Article in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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  14. Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Neha JariwalaDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Bernice BenoitDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andrew V KossenkovThe Wistar Institute, Philadelphia, Pennsylvania, USA.
Landon K OetjenDepartment of Medicine, Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, USA.
Timothy M WhelanDepartment of Medicine, Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, USA; The Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA.
Christine M CornejoDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Junko TakeshitaDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Brian S KimDepartment of Medicine, Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, USA; The Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Louise C ShoweThe Wistar Institute, Philadelphia, Pennsylvania, USA.
Maria WysockaDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: mwysocka@mail.med.upenn.edu.
Alain H RookDepartment of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USWashington University in St. Louis · USThe Wistar Institute · USDrexel University · US

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Dario C Altieri · 1985 to 2026
$75.9M
Targeted Combination Therapy for MelanomaP50CA174523 · NCI · WISTAR INSTITUTE · PI HERLYN, MEENHARD F · 2014 to 2018
$11.1M
Transforming the diagnosis and care of patients with CTCL using TCR sequencingR01CA203721 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI CLARK, RACHAEL ANN, KUPPER, THOMAS S. · 2016 to 2020
$3.4M
HDAC Inhibitors and CTCLR01CA132098 · NCI · WISTAR INSTITUTE · PI SHOWE, LOUISE C. · 2009 to 2013
$2.0M
Integrative Approach to Comprehensive Analysis of High Throughput Data on a Cancer Center LevelR50CA211199 · NCI · WISTAR INSTITUTE · PI Andrew V Kossenkov · 2016 to 2026
$1.6M
Racial Disparities in the Treatment of Psoriasis: A Mixed Methods ApproachK23AR068433 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI TAKESHITA, JUNKO · 2015 to 2019
$726k
Innate Immune Regulation of Skin InflammationK08AR065577 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2014 to 2018
$711k
NCI NIH HHS P30 CA010815NCI NIH HHS P50 CA174523NCI NIH HHS R01 CA132098NCI NIH HHS R01 CA203721NCI NIH HHS R50 CA211199NIAMS NIH HHS K08 AR065577NIAMS NIH HHS K23 AR068433
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorCD4-Positive T-LymphocytesGene Expression ProfilingHumansIkaros Transcription FactorLymphocyte ActivationMicroarray AnalysisMycosis FungoidesNeoplasm StagingReceptors, ImmunologicRNA, MessengerSezary SyndromeSkinSkin NeoplasmsTumor BurdenBiomarkers, TumorIkaros Transcription FactorIKZF2 protein, humanReceptors, ImmunologicRNA, MessengerTIGIT protein, human

Identifiers

PMID27592800
PMCPMC5358509
OpenAlexW2514407904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.