Evidence map›Paper›PMID 27592634›Full record

ArticleChronobiology international2016

Dim light at night prior to adolescence increases adult anxiety-like behaviors.

Yasmine M Cissé, Juan Peng, Randy J Nelson

Abstract read
In one paragraph

Article in Chronobiology international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Disrupted circadian rhythms and mental health.Handbook of clinical neurology · 2021
    Review
  14. Article
  15. Circadian rhythm disruption and mental health.Translational psychiatry · 2020
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yasmine M Cisséa Department of Neuroscience, Neuroscience Research Institute, Behavioral Neuroendocrinology Group , The Ohio State University Wexner Medical Center , Columbus , OH , USA.
Juan Pengb Center for Biostatistics , The Ohio State University , Columbus , OH , USA.
Randy J Nelsona Department of Neuroscience, Neuroscience Research Institute, Behavioral Neuroendocrinology Group , The Ohio State University Wexner Medical Center , Columbus , OH , USA.

Funding

Comprehensive Training in Oral &Craniofacial SciencesT32DE014320 · NIDCR · OHIO STATE UNIVERSITY · PI SHERIDAN, JOHN F · 2001 to 2022
$10.2M
Ohio State Neuroscience Centr CoreP30NS045758 · NINDS · OHIO STATE UNIVERSITY · PI OBRIETAN, KARL H · 2004 to 2015
$7.7M
NIDCR NIH HHS T32 DE014320NINDS NIH HHS P30 NS045758
6 · The paper itself

Abstract

Dim light at night (dLAN) disrupts circadian organization and influences adult behavior. We examined early dLAN exposure on adult affective responses. Beginning 3 (juvenile) or 5 weeks (adolescent) of age, mice were maintained in standard light-dark cycles or exposed to nightly dLAN (5 lx) for 5 weeks, then anxiety-like and fear responses were assessed. Hypothalami were collected around the clock to assess core clock genes. Exposure to dLAN at either age increased anxiety-like responses in adults. Clock and Rev-ERB expression were altered by exposure to dLAN. In contrast to adults, dLAN exposure during early life increases anxiety and fear behavior.

Indexed as

LightAgingAnimalsAnxietyBehavior, AnimalCircadian RhythmFemaleMaleMiceMotor ActivityPhotoperiodanxietycircadian disruptionearly lifefear conditioningLight at night

Identifiers

PMID27592634
PMCPMC5568526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.