Evidence map›Paper›PMID 27592386›Full record

ArticleNitric oxide : biology and chemistry2016

Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge.

Binglan Yu, Aron H Blaesi, Noel Casey, Grigory Raykhtsaum, Luca Zazzeron, Rosemary Jones, Alexander Morrese, Danil Dobrynin, Rajeev Malhotra, Donald B Bloch and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nitric oxide : biology and chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Nitric oxide: Clinical applications in critically ill patients.Nitric oxide : biology and chemistry · 2022
    Review
  4. Article
  5. Article
  6. Inhaled nitric oxide.British journal of pharmacology · 2019
    Review
  7. Article
  8. Pulmonary Delivery of Therapeutic and Diagnostic Gases.Journal of aerosol medicine and pulmonary drug delivery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Binglan YuAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Aron H BlaesiAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Noel CaseyCenter for Biometals & Metallomics, Boston University School of Medicine, College of Engineering, Photonics Center, and Alzheimer's Disease Center, Boston, MA 02118, USA.
Grigory RaykhtsaumDepartment of Metallurgy, LeachGarner, Attleboro, MA 02703, USA.
Luca ZazzeronAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Rosemary JonesAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Alexander MorreseApplied Physics Laboratory, A. J. Drexel Plasma Institute, Drexel University, Camden, NJ 08103, USA.
Danil DobryninApplied Physics Laboratory, A. J. Drexel Plasma Institute, Drexel University, Camden, NJ 08103, USA.
Rajeev MalhotraCardiology Division and Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Donald B BlochAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Lee E GoldsteinCenter for Biometals & Metallomics, Boston University School of Medicine, College of Engineering, Photonics Center, and Alzheimer's Disease Center, Boston, MA 02118, USA; Boston University School of Medicine, College of Engineering, Photonics Center, and Alzheimer's Disease Center, Boston, MA 02118, USA.
Warren M ZapolAnesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: wzapol@mgh.harvard.edu.
Massachusetts General Hospital · USBoston University · USDrexel University · USHarvard University · US

Funding

Boston Biomedical Innovation CenterU54HL119145 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLAN, DAVID E., LOSCALZO, JOSEPH · 2013 to 2021
$18.8M
The Role of Bone Morphogenetic Proteins in Vascular CalcificationK08HL111210 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MALHOTRA, RAJEEV · 2014 to 2018
$796k
Producing Nitric Oxide by Pulsed Electrical Discharge in Air for Inhalation TherapyR21HL130956 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI YU, BINGLAN · 2016 to 2017
$444k
MAGNETIC SECTOR FIELD HIGH RESOLUTION MASS SPECTROMETERS10RR021131 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLDSTEIN, LEE E · 2006 to 2006
$423k
NCRR NIH HHS S10 RR021131NHLBI NIH HHS K08 HL111210NHLBI NIH HHS R21 HL130956NHLBI NIH HHS U54 HL119145
6 · The paper itself

Abstract

Inhalation of nitric oxide (NO) produces selective pulmonary vasodilation without dilating the systemic circulation. However, the current NO/N

Indexed as

Administration, InhalationAir FiltersAir PollutantsAnimalsDrug ContaminationElectrodesFiltrationIridiumLungMaleMetals, HeavyMiceMice, Inbred C57BLNitric OxideTemperatureAir PollutantsIridiumMetals, HeavyNitric OxideIridium electrodeMetal particlesNitric oxidePulsed electrical discharge

Identifiers

PMID27592386
PMCPMC5079831
OpenAlexW2507869129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.