Trial reportBehaviour research and therapy2016
Defined symptom-change trajectories during acute-phase cognitive therapy for depression predict better longitudinal outcomes.
Trial report in Behaviour research and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Effects of Transdiagnostic Cognitive Behavioural Therapy on Long-Term Quality of Life: A Causal Mediation Analysis Across Anxiety and Depressive Symptoms.Depression and anxiety · 2026Trial
- The Duration-Adjusted Reliable Change Index: Defining Clinically Relevant Symptom Changes of Varying Durations.Assessment · 2024Article
- Cognitive outcomes are differentially associated with depression severity trajectories during psychotherapy treatment for late life major depressive disorder.International journal of geriatric psychiatry · 2022Article
- Case Report: Individualization of Intensive Transactional Analysis Psychotherapy on the Basis of Ego Strength.Frontiers in psychology · 2021Article
- A complex systems approach to the study of change in psychotherapy.BMC medicine · 2020Article
- The Role of Dyadic Discord in Outcomes in Acute Phase Cognitive Therapy for Adults With Recurrent Major Depressive Disorder.Behavior therapy · 2019Article
- Estimating outcome probabilities from early symptom changes in cognitive therapy for recurrent depression.Journal of consulting and clinical psychology · 2019Article
- Trajectories of depression and anxiety symptom change during psychological therapy.Journal of affective disorders · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundAcute-phase cognitive therapy (CT) is an efficacious treatment for major depressive disorder (MDD), but responders experience varying post-acute outcomes (e.g., relapse vs. recovery). Responders' symptom-change trajectories during response to acute-phase CT may predict longer term outcomes.
methodWe studied adult outpatients (N = 220) with recurrent MDD who responded to CT but had residual symptoms. Responders with linear (steady improvement), log-linear (quicker improvement earlier and slower later), one-step (a single, relatively large, stable improvement between adjacent assessments), or undefined (not linear, log-linear, or one-step) symptom trajectories were assessed every 4 months for 32 additional months.
resultsDefined (linear, log-linear, one-step) versus undefined acute-phase trajectories predicted lower depressive symptoms (d = 0.36), lower weekly probability of being in a major depressive episode (OR = 0.46), higher weekly probabilities of remission (OR = 1.93) and recovery (OR = 2.35), less hopelessness (d = 0.41), fewer dysfunctional attitudes (d = 0.31), and better social adjustment (d = 0.32) for 32 months after acute-phase CT. Differences among defined trajectory groups were nonsignificant.
conclusionsResponding to acute-phase CT with a defined trajectory (orderly pattern) of symptom reduction predicts better longer term outcomes, but which defined trajectory (linear, log-linear, or one-step) appears unimportant. Frequent measurement of depressive symptoms to identify un/defined CT response trajectories may clarify need for continued clinical monitoring and treatment.
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