ArticleAlcoholism, clinical and experimental research2016
Do Alcohol Relapse Episodes During Treatment Predict Long-Term Outcomes? Investigating the Validity of Existing Definitions of Alcohol Use Disorder Relapse.
Article in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Efficacy of A Virtual Agent-Based Digital Intervention (Echo App V2.0) for Patients With Alcohol Use Disorder: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- The patterns of relapse and abstinence: using machine learning to identify a multidimensional signature of long-term outcome after inpatient alcohol withdrawal treatment.Frontiers in psychiatry · 2026Article
- Craving changes in first 14 days of addiction treatment: an outcome predictor of 5 years substance use status?Translational psychiatry · 2024Article
- Altered Expression of Neuroplasticity-Related Genes in Alcohol Addiction and Treatment.International journal of molecular sciences · 2024Article
- Relapse on the Road to Recovery: Learning the Lessons of Failure on the Way to Successful Behavior Change.Journal of health service psychology · 2022Article
- Within-AUD outpatient treatment heavy drinking transitions and associations with long-term outcomes.Drug and alcohol dependence · 2021Article
- The Clinical Course of Alcohol Use Disorder Depicted by Digital Biomarkers.Frontiers in digital health · 2021Article
- Reductions in Drinking Predict Increased Distress: Between- and Within-Person Associations between Alcohol Use and Psychological Distress During and Following Treatment.Alcoholism, clinical and experimental research · 2020Article
- Anterior Insular Cortex is Critical for the Propensity to Relapse Following Punishment-Imposed Abstinence of Alcohol Seeking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Profiles of recovery from alcohol use disorder at three years following treatment: can the definition of recovery be extended to include high functioning heavy drinkers?Addiction (Abingdon, England) · 2019Article
- Course of remission from and relapse to heavy drinking following outpatient treatment of alcohol use disorder.Drug and alcohol dependence · 2018Article
- Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats.Alcoholism, clinical and experimental research · 2017Article
- Alcohol Relapse and Change Needs a Broader View than Counting Drinks.Alcoholism, clinical and experimental research · 2017Article
- Assessing the Predictive Validity of the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) in Alaska Native and American Indian People.Journal of addiction medicineArticle
- Key Terms and Concepts in Alcohol Use and Problems: A Critical Evaluation.Substance use : research and treatmentArticle
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Authors and funding
6 authors.
Funding
Abstract
backgroundThe construct of relapse is used widely in clinical research and practice of alcohol use disorder (AUD) treatment. The purpose of this study was to test the predictive validity of commonly appearing definitions of AUD relapse in the empirical literature.
methodsSecondary analyses of data from Project MATCH and COMBINE were conducted using 7 definitions of "relapse" based on drinking quantity within a single drinking episode: any drinking; at least 4/5 drinks for women/men; at least 4.3/7.1 drinks for women/men; at least 6/7 drinks for women/men; at least 6 drinks; at least 7/9 drinks for women/men; and at least 8/10 drinks for women/men. Relapse was used to predict alcohol consumption, related consequences, and nonconsumption outcomes (quality of life, psychosocial functioning) at the end of treatment and up to 1 year posttreatment.
resultsRegression analyses indicated within-treatment relapse definitions significantly predicted end-of-treatment alcohol consumption and alcohol-related consequences. Heavy drinking definitions were generally more predictive than the any drinking definition, but no single heavy drinking definition was consistently a better predictor of outcomes. Relapse definitions were less predictive of longer-term alcohol-related outcomes and both shorter- and longer-term nonconsumption outcomes, including health and psychosocial functioning.
conclusionsOne particular definition of relapse did not consistently stand out as the best predictor. Advances in AUD research may require reconceptualization of relapse as a multifaceted dynamic process and may consider a wider range of relevant behaviors (e.g., health and psychosocial functioning) when examining the change process in individuals with AUD.
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