Evidence map›Paper›PMID 27591258›Full record

ArticleJournal of cell science2016

Mutant IP3 receptors attenuate store-operated Ca2+ entry by destabilizing STIM-Orai interactions in Drosophila neurons.

Sumita Chakraborty, Bipan K Deb, Tetyana Chorna, Vera Konieczny, Colin W Taylor, Gaiti Hasan

Abstract read
In one paragraph

Article in Journal of cell science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. The machinery of healthy vasoconstriction: an overview.Pflugers Archiv : European journal of physiology · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Store-Operated Calcium Channels: From Function to Structure and Back Again.Cold Spring Harbor perspectives in biology · 2020
    Review
  9. Article
  10. Target Molecules of STIM Proteins in the Central Nervous System.Frontiers in molecular neuroscience · 2020
    Review
  11. The role of Stim1 in the progression of lupus nephritis in mice.International journal of clinical and experimental pathology · 2020
    Article
  12. Orai1 Promotes Osteosarcoma Metastasis by Activating the Ras-Rac1-WAVE2 Signaling Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  13. Structure and Function of IPCold Spring Harbor perspectives in biology · 2019
    Review
  14. Article
  15. Article
  16. A Multicomponent Neuronal Response Encodes the Larval Decision to Pupariate upon Amino Acid Starvation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  17. Molecular physiology and pathophysiology of stromal interaction molecules.Experimental biology and medicine (Maywood, N.J.) · 2018
    Review
  18. CaNature communications · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sumita ChakrabortyNational Centre for Biological Sciences, Tata Institute for Fundamental Research, Bellary Road, Bangalore 560065, India Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
Bipan K DebNational Centre for Biological Sciences, Tata Institute for Fundamental Research, Bellary Road, Bangalore 560065, India.
Tetyana ChornaNational Centre for Biological Sciences, Tata Institute for Fundamental Research, Bellary Road, Bangalore 560065, India.ORCID 0000-0003-1304-0004
Vera KoniecznyDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
Colin W TaylorDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK cwt1000@cam.ac.uk gaiti@ncbs.res.in.ORCID 0000-0001-7771-1044
Gaiti HasanNational Centre for Biological Sciences, Tata Institute for Fundamental Research, Bellary Road, Bangalore 560065, India cwt1000@cam.ac.uk gaiti@ncbs.res.in.

Funding

Wellcome Trust 101844
6 · The paper itself

Abstract

Store-operated Ca

Indexed as

AnimalsCalciumCalcium SignalingCell MembraneChickensDrosophila melanogasterDrosophila ProteinsInositol 1,4,5-Trisphosphate ReceptorsModels, BiologicalMutant ProteinsNeuronsORAI1 ProteinStromal Interaction Molecule 1VertebratesCalciumDrosophila ProteinsInositol 1,4,5-Trisphosphate ReceptorsMutant Proteinsolf186-F protein, DrosophilaORAI1 ProteinStim protein, DrosophilaStromal Interaction Molecule 1Ca2+ signallingDrosophilaIP3 receptorOraiSTIMStore-operated Ca2+ entry

Identifiers

PMID27591258
PMCPMC5087660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.