Evidence map›Paper›PMID 27591209›Full record

ArticleHuman factors2016

Package Design Affects Accuracy Recognition for Medications.

Tor Endestad, Laura A Wortinger, Steinar Madsen, Sigurd Hortemo

Open access · bronzeAbstract read
In one paragraph

Article in Human factors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tor EndestadUniversity of Oslo, Norway tor.endestad@psykologi.uio.no.
Laura A WortingerUniversity of Oslo, Norway.
Steinar MadsenUniversity of Oslo, Norway.
Sigurd HortemoNorwegian Medicines Agency, Oslo, Norway.
University of Oslo · NONorwegian Medicines Agency · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur aim was to test if highlighting and placement of substance name on medication package have the potential to reduce patient errors.

backgroundAn unintentional overdose of medication is a large health issue that might be linked to medication package design. In two experiments, placement, background color, and the active ingredient of generic medication packages were manipulated according to best human factors guidelines to reduce causes of labeling-related patient errors.

methodIn two experiments, we compared the original packaging with packages where we varied placement of the name, dose, and background of the active ingredient. Age-relevant differences and the effect of color on medication recognition error were tested. In Experiment 1, 59 volunteers (30 elderly and 29 young students), participated. In Experiment 2, 25 volunteers participated.

resultsThe most common error was the inability to identify that two different packages contained the same active ingredient (young, 41%, and elderly, 68%). This kind of error decreased with the redesigned packages (young, 8%, and elderly, 16%). Confusion errors related to color design were reduced by two thirds in the redesigned packages compared with original generic medications.

conclusionProminent placement of substance name and dose with a band of high-contrast color support recognition of the active substance in medications. APPLICATION: A simple modification including highlighting and placing the name of the active ingredient in the upper right-hand corner of the package helps users realize that two different packages can contain the same active substance, thus reducing the risk of inadvertent medication overdose.

Indexed as

AdultAgedAge FactorsColor PerceptionDrug LabelingDrug PackagingHumansPattern Recognition, VisualRecognition, PsychologyYoung Adultcognitiondesigning for the elderlyhuman errormemorypackage labelingpatient safety

Identifiers

PMID27591209
PMCPMC5570154
OpenAlexW2509411866

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.