Evidence map›Paper›PMID 27591147›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2017

On the Stability of BOLD fMRI Correlations.

Timothy O Laumann, Abraham Z Snyder, Anish Mitra, Evan M Gordon, Caterina Gratton, Babatunde Adeyemo, Adrian W Gilmore, Steven M Nelson, Jeff J Berg, Deanna J Greene and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 328 papers.

0numbers the graph read from it
0cells of the map it votes in
328citing papers in PubMed
41.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

328 citing papers in PubMed, 577 citations in OpenAlex.

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  15. The individuality of single-frame functional brain connectivity.bioRxiv : the preprint server for biology · 2026
    Article
  16. Considerations for conducting developmental neuroimaging research on mental health topics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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268 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Timothy O LaumannDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Abraham Z SnyderDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Anish MitraDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Evan M GordonVISN 17 Center of Excellence for Research on Returning War Veterans, Waco, TX 76711, USA.
Caterina GrattonDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Babatunde AdeyemoDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Adrian W GilmoreDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63110, USA.
Steven M NelsonVISN 17 Center of Excellence for Research on Returning War Veterans, Waco, TX 76711, USA.
Jeff J BergDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63110, USA.
Deanna J GreeneDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
John E McCarthyDepartment of Mathematics, Washington University in St. Louis, St. Louis, MO 63130, USA.
Enzo TagliazucchiDepartmen of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Helmut LaufsInstitute for Medical Psychology, Christian-Albrechts-Universitat zu Kiel, Kiel, Germany.
Bradley L SchlaggarDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Nico U F DosenbachDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Steven E PetersenDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Washington University in St. Louis · USKiel University · DEThe University of Texas at Dallas · USVA Heart of Texas Health Care Network · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
PEDIATRIC BRAIN INJURY RECOVERY VIA USE-DRIVEN FUNCTIONAL NETWORK REORGANIZATIONK23NS088590 · NINDS · WASHINGTON UNIVERSITY · PI DOSENBACH, NICO · 2015 to 2019
$886k
NCATS NIH HHS UL1 TR002345NIAID NIH HHS T32 AI007172NICHD NIH HHS U54 HD087011NINDS NIH HHS K23 NS088590
6 · The paper itself

Abstract

Measurement of correlations between brain regions (functional connectivity) using blood oxygen level dependent (BOLD) fMRI has proven to be a powerful tool for studying the functional organization of the brain. Recently, dynamic functional connectivity has emerged as a major topic in the resting-state BOLD fMRI literature. Here, using simulations and multiple sets of empirical observations, we confirm that imposed task states can alter the correlation structure of BOLD activity. However, we find that observations of "dynamic" BOLD correlations during the resting state are largely explained by sampling variability. Beyond sampling variability, the largest part of observed "dynamics" during rest is attributable to head motion. An additional component of dynamic variability during rest is attributable to fluctuating sleep state. Thus, aside from the preceding explanatory factors, a single correlation structure-as opposed to a sequence of distinct correlation structures-may adequately describe the resting state as measured by BOLD fMRI. These results suggest that resting-state BOLD correlations do not primarily reflect moment-to-moment changes in cognitive content. Rather, resting-state BOLD correlations may predominantly reflect processes concerned with the maintenance of the long-term stability of the brain's functional organization.

Indexed as

Image Processing, Computer-AssistedMagnetic Resonance ImagingAdultBrainBrain MappingCerebrovascular CirculationFemaleHumansMaleNeural PathwaysOxygenRestYoung AdultOxygenBOLD fMRIdynamicsfunctional connectivitynonstationarityresting state

Identifiers

PMID27591147
PMCPMC6248456
OpenAlexW2516718464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.