Evidence map›Paper›PMID 27590997›Full record

ArticleGut2017

Shoumin Zhu, Mohammed Soutto, Zheng Chen, DunFa Peng, Judith Romero-Gallo, Uma S Krishna, Abbes Belkhiri, M Kay Washington, Richard Peek, Wael El-Rifai

Open access · greenAbstract read
In one paragraph

Article in Gut, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Update on the pathogenesis and clinical management ofWorld journal of gastrointestinal pathophysiology · 2025
    Review
  4. Article
  5. Article
  6. Helicobacter Pylori-induced BRD2 mInternational journal of biological sciences · 2025
    Article
  7. The intersection ofFrontiers in cellular and infection microbiology · 2025
    Review
  8. Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shoumin ZhuDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Mohammed SouttoDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Zheng ChenDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
DunFa PengDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Judith Romero-GalloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Uma S KrishnaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Abbes BelkhiriDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
M Kay WashingtonDepartment of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Richard PeekDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Wael El-RifaiDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Understanding and Controlling p120 Dysfunction in CRCP50CA095103 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2002 to 2017
$33.6M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 2009 to 2026
$27.5M
H.Pylori Relationship to Digestive Diseases and CancerR01CA077955 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2003 to 2026
$9.7M
Helicobacter Pylori and Gastrointestinal BiologyR01DK058587 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEK, RICHARD M. · 2001 to 2024
$7.8M
Targets of Gene Overexpression at 17q in Gastric Tumorigenesis: Darpp32R01CA093999 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI EL-RIFAI, WAEL · 2002 to 2017
$4.5M
BLRD Research Career Scientist Award ApplicationIK6BX003787 · VA · VETERANS HEALTH ADMINISTRATION · PI WAEL EL-RIFAI · 2017 to 2026
–
BLRD VA IK6 BX003787NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA095103NCI NIH HHS R01 CA077955NCI NIH HHS R01 CA093999NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK058587
6 · The paper itself

Abstract

objective

designThe study used

resultsOur results indicated that

conclusionsGiven the high frequency of DARPP-32 overexpression and its prosurvival oncogenic functions, the induction of DARPP-32 expression following

Indexed as

Helicobacter pyloriAnimalsCell DeathCell Line, TumorCell SurvivalDopamine and cAMP-Regulated Phosphoprotein 32Gastric MucosaHelicobacter InfectionsHumansMiceNF-kappa BPromoter Regions, GeneticProto-Oncogene Proteins c-aktRNA, MessengerSignal TransductionStomach NeoplasmsDopamine and cAMP-Regulated Phosphoprotein 32NF-kappa BProto-Oncogene Proteins c-aktRNA, MessengerTumor Necrosis Factor-alphaGASTRIC CANCERGASTRIC INFLAMMATIONHELICOBACTER PYLORI

Identifiers

PMID27590997
PMCPMC5334457
OpenAlexW2512823454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.