Evidence map›Paper›PMID 27590583›Full record

ReviewBiochemical and biophysical research communications2017

Calcium and Parkinson's disease.

D James Surmeier, Paul T Schumacker, Jaime D Guzman, Ema Ilijic, Ben Yang, Enrico Zampese

Abstract readReview
In one paragraph

Review in Biochemical and biophysical research communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 192 citations in OpenAlex.

  1. Review
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  6. Article
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  9. Disease-modifying, multidimensional efficacy of putaminal CaMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  10. Article
  11. Article
  12. Review
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  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. NOX2-TRPM2 coupling promotes ZnScientific reports · 2024
    Article
  20. Review

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D James SurmeierDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA. Electronic address: j-surmeier@northwestern.edu.
Paul T SchumackerDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA.
Jaime D GuzmanDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA.
Ema IlijicDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA.
Ben YangDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA.
Enrico ZampeseDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, 60611, Illinois, USA.
Northwestern University · US

Funding

SYNAPTIC CONTROLOF PALLIDAL ACTIVITYP50NS047085 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SURMEIER, DALTON JAMES · 2003 to 2018
$19.2M
Metabolic Regulation of Pulmonary Vascular RemodelingR01HL122062 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHUMACKER, PAUL T · 2014 to 2017
$2.0M
NHLBI NIH HHS R01 HL122062NINDS NIH HHS P50 NS047085
6 · The paper itself

Abstract

Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Its causes are poorly understood and there is no proven therapeutic strategy for slowing disease progression. The core motor symptoms of PD are caused by the death of dopaminergic neurons in the substantia nigra pars compacta (SNc). In these neurons, Ca

Indexed as

AnimalsCalciumCalcium Channels, L-TypeCytosolHumansIon TransportNeuronsParkinson DiseaseCalciumCalcium Channels, L-TypeDopamineElectrophysiologyEndoplasmic reticulumMitochondriaOxidant stressSubstantia nigraTwo photon microscopy

Identifiers

PMID27590583
PMCPMC5449761
OpenAlexW2516276224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.