ArticleBMC oral health2016
Low vitamin D status strongly associated with periodontitis in Puerto Rican adults.
Article in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 6 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Vitamin D deficiency and oral health: a systematic review of literature.BMC oral health · 2025Pooled it
- Vitamin intake and periodontal disease: a meta-analysis of observational studies.BMC oral health · 2024Pooled it
- Association of vitamin D in individuals with periodontitis: an updated systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Pooled it
- The Role of Vitamins in Oral Health. A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance.Molecules (Basel, Switzerland) · 2018Pooled it
- Impact of Adjunctive Air-Polishing on Periodontal Status in Patients with Low Vitamin DJournal of clinical medicine · 2025Article
- Evaluation of Serum Vitamin D and C Concentrations in Cats With Gingivostomatitis.Veterinary medicine and science · 2025Article
- Article
- Effect of sleeve gastrectomy on the levels of oral volatile sulfur compounds and halitosis-related bacteria.The Saudi dental journal · 2024Article
- Review
- Periodontal Disease and Other Adverse Health Outcomes Share Risk Factors, including Dietary Factors and Vitamin D Status.Nutrients · 2023Review
- Comparison of serum levels of vitamin D in periodontitis patients with and without type 2 diabetes and healthy subjects.Clinical and experimental dental research · 2022Article
- The Relationship Between Low Serum Vitamin D Level and Early Dental Implant Failure: A Systematic Review.Cureus · 2022Review
- The association between vitamin D level and periodontal disease in Saudi population, a preliminary study.The Saudi dental journal · 2021Article
- Association between periodontitis and vitamin D status: A case-control study.Saudi journal of biological sciences · 2021Article
- Expanding the Capabilities of Nutrition Research and Health Promotion Through Mobile-Based Applications.Advances in nutrition (Bethesda, Md.) · 2021Article
- Tropical Oral Disease: Analysing Barriers, Burden, Nutrition, Economic Impact, and Inequalities.Frontiers in nutrition · 2021Review
- Low serum 25-hydroxyvitamin D levels, tooth loss, and the prevalence of severe periodontitis in Koreans aged 50 years and older.Journal of periodontal & implant science · 2020Article
- Relationship between risk markers for cardiovascular disease and peri-implant diseases.International journal of implant dentistry · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundPeriodontitis and vitamin D deficiency are both highly prevalent in Puerto Rico. The aim of this pilot study was to evaluate the association between vitamin D levels and periodontal disease in Puerto Rican adults.
methodsA sex-, age-, and BMI-matched case-control, cross-sectional study was conducted on 24 cases of moderate/severe periodontitis and 24 periodontally healthy controls aged 35 to 64 years. Each participant completed a socio-demographic questionnaire, underwent a full-mouth periodontal examination and provided blood sample to measure serum 25-hydroxyvitamin D (25 (OH) D) levels to assess vitamin D status.
resultsA total of 19 matched case-control pairs (28 females, 10 males) completed the study. Mean serum 25 (OH) D levels were significantly lower in cases (18.5 ± 4.6 ng/ml) than in controls (24.2 ± 7.1 ng/ml; p = 0.006). Lower odds of periodontal disease were observed per unit of 25 (OH) D level (OR 0.885; 95 % CI 0.785, 0.997; p < 0.05).
conclusionsLower serum vitamin D levels are significantly associated with periodontitis in Puerto Rican adults.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.