ArticleThe Journal of biological chemistry2016
A Novel F420-dependent Thioredoxin Reductase Gated by Low Potential FAD: A TOOL FOR REDOX REGULATION IN AN ANAEROBE.
Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Pilot Scale Production of a FBiotechnology journal · 2025Article
- Catalytic Activity of the Archetype from Group 4 of the FTR-like Ferredoxin:Thioredoxin Reductase Family Is Regulated by UniqueBiochemistry · 2024Article
- A Reduced FJournal of bacteriology · 2022Article
- Structural and Biochemical Characterization of Thioredoxin-2 fromAntioxidants (Basel, Switzerland) · 2021Article
- On the diversity of FProteins · 2021Article
- Cofactor F420: an expanded view of its distribution, biosynthesis and roles in bacteria and archaea.FEMS microbiology reviews · 2021Article
- Unexpected diversity of ferredoxin-dependent thioredoxin reductases in cyanobacteria.Plant physiology · 2021Article
- Redox and Thiols in Archaea.Antioxidants (Basel, Switzerland) · 2020Review
- A Genetic System forFrontiers in microbiology · 2019Article
- Ferredoxin-linked flavoenzyme defines a family of pyridine nucleotide-independent thioredoxin reductases.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Coenzyme FJournal of bacteriology · 2018Article
- Crystal Structure of the Apo-Form of NADPH-Dependent Thioredoxin Reductase from a Methane-Producing Archaeon.Antioxidants (Basel, Switzerland) · 2018Article
- Methionine Sulfoxide Reductases of Archaea.Antioxidants (Basel, Switzerland) · 2018Review
- Metabolic shift at the class level sheds light on adaptation of methanogens to oxidative environments.The ISME journal · 2018Article
- Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- A Reexamination of Thioredoxin Reductase fromACS omega · 2017Article
- Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase fromFrontiers in microbiology · 2017Article
- Methanosarcina acetivorans utilizes a single NADPH-dependent thioredoxin system and contains additional thioredoxin homologues with distinct functions.Microbiology (Reading, England) · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A recent report suggested that the thioredoxin-dependent metabolic regulation, which is widespread in all domains of life, existed in methanogenic archaea about 3.5 billion years ago. We now show that the respective electron delivery enzyme (thioredoxin reductase, TrxR), although structurally similar to flavin-containing NADPH-dependent TrxRs (NTR), lacked an NADPH-binding site and was dependent on reduced coenzyme F
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