Evidence map›Paper›PMID 27590224›Full record

ArticleHandbook of experimental pharmacology2017

The Mitochondrial Permeability Transition Pore and ATP Synthase.

Gisela Beutner, Kambiz N Alavian, Elizabeth A Jonas, George A Porter

Erratum issuedAbstract read
In one paragraph

Article in Handbook of experimental pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  13. The Joint Influence of TlInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gisela BeutnerDivision of Cardiology, Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Ave., Box 631, Rochester, 14642, NY, USA.
Kambiz N AlavianDivision of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
Elizabeth A JonasDepartment of Internal Medicine, Section of Endocrinology, Yale University, New Haven, CT, USA.
George A PorterDivision of Cardiology, Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Ave., Box 631, Rochester, 14642, NY, USA. george_porter@urmc.rochester.edu.

Funding

Mitochondrial Ion Channels in Hypoxic NeuronsR37NS045876 · NINDS · YALE UNIVERSITY · PI Elizabeth Ann Jonas · 2014 to 2026
$4.9M
Mitochondrial control of protein translation in Fragile XR01NS112706 · NINDS · YALE UNIVERSITY · PI Elizabeth Ann Jonas, Pawel Licznerski · 2019 to 2026
$3.6M
Mitochondrial ion channels in hypoxic neuronsR01NS045876 · NINDS · YALE UNIVERSITY · PI JONAS, ELIZABETH ANN · 2004 to 2013
$3.3M
Role of DJ1 in mitochondrial biogenergetics and neuronal metabolismR01NS081746 · NINDS · YALE UNIVERSITY · PI JONAS, ELIZABETH ANN · 2014 to 2018
$2.2M
NIH HHS NS045876NIH HHS NS081746NINDS NIH HHS R01 NS045876NINDS NIH HHS R01 NS081746NINDS NIH HHS R01 NS112706NINDS NIH HHS R37 NS045876
6 · The paper itself

Abstract

Mitochondrial ATP generation by oxidative phosphorylation combines the stepwise oxidation by the electron transport chain (ETC) of the reducing equivalents NADH and FADH

Indexed as

Adenosine TriphosphateAnimalsApoptosisElectron TransportEnergy MetabolismHumansMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesAdenosine TriphosphateMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesATP synthaseBioenergeticsElectron transport chainEmbryonic heartMitochondriaPermeability transition pore

Identifiers

PMID27590224
PMCPMC7439278

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.