ReviewTrends in neurosciences2016
Thalamic Inhibition: Diverse Sources, Diverse Scales.
Review in Trends in neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed.
- Metabotropic Glutamatergic Signaling Adaptively Controls Trans-thalamic Communication.bioRxiv : the preprint server for biology · 2026Article
- Hierarchical Reconfiguration of Neurocognitive Task Set Representations Mediates Cognitive Flexibility.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Toward a Neurobiological Model of Gestalt Confluence: Thalamocortical Integration as a Hypothetical Framework for Contact Interruption.Brain sciences · 2026Article
- Data-driven mouse motor thalamus model reveals topography and spatial weight scaling govern spindle dynamics.Communications biology · 2026Article
- Temporally Coordinated Activity among Motor Cortex, Thalamus, and Thalamic Reticular Nucleus Neurons during Rat Forelimb Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Modulation and Gating of Transthalamic and Subcortical Pathways through Somatosensory Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Thalamic reticular neurons provide cell type-specific modulation of sound processing in the auditory thalamus.PLoS biology · 2026Article
- Short-Term Modulation of Epileptic Network with Low-Frequency Thalamic Stimulation.medRxiv : the preprint server for health sciences · 2025Article
- The neural basis for uncertainty processing in hierarchical decision making.Nature communications · 2025Article
- Parvalbumin and Somatostatin Neurons in the Thalamic Reticular Nucleus Modulate Visual Information Processing in V1 of Mouse.Neuroscience bulletin · 2025Article
- Closed-Loop Connectivity Best Supports Angular Tuning and Sleep Dynamics in a Biophysical Thalamocortical Circuit Model.bioRxiv : the preprint server for biology · 2025Article
- Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus.Nature communications · 2025Article
- Developing algorithmic psychiatry via multi-level spanning computational models.Cell reports. Medicine · 2025Review
- Integrated Classification of Cortical Cells and Quantitative Projectomic Mapping Unveil Organizational Principles of Brain-Wide Connectomes at Single Cell Level.bioRxiv : the preprint server for biology · 2025Article
- Computational modeling of frequency-dependent neocortical response to thalamic neurostimulation in epilepsy.PLoS computational biology · 2025Article
- A cortico-subcortical loop for motor control via the pontine reticular formation.Cell reports · 2025Article
- The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus.Brain imaging and behavior · 2025Article
- FOXP2-immunoreactive corticothalamic neurons in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systems.iScience · 2025Article
- Inhibition of thalamic relay nuclei scales the aperiodic and alpha band oscillations associated with arousal during naturalistic stimulus viewing.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Regulation of neuronal fate specification and connectivity of the thalamic reticular nucleus by the Ascl1-Isl1 transcriptional cascade.Cellular and molecular life sciences : CMLS · 2024Article
57 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
The thalamus is the major source of cortical inputs shaping sensation, action, and cognition. Thalamic circuits are targeted by two major inhibitory systems: the thalamic reticular nucleus (TRN) and extrathalamic inhibitory (ETI) inputs. A unifying framework of how these systems operate is currently lacking. Here, we propose that TRN circuits are specialized to exert thalamic control at different spatiotemporal scales. Local inhibition of thalamic spike rates prevails during attentional selection, whereas global inhibition more likely prevails during sleep. In contrast, the ETI (arising from basal ganglia, zona incerta (ZI), anterior pretectum, and pontine reticular formation) provides temporally precise and focal inhibition, impacting spike timing. Together, these inhibitory systems allow graded control of thalamic output, enabling thalamocortical operations to dynamically match ongoing behavioral demands.
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