ArticleSensors (Basel, Switzerland)2016
A Simple BODIPY-Based Viscosity Probe for Imaging of Cellular Viscosity in Live Cells.
Article in Sensors (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Lighting Up Biology: GFP-Inspired Fluorescent Probes for Sensing and Imaging.Journal of the American Chemical Society · 2026Article
- Chemical propulsion of hemozoin crystal motion in malaria parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- An update on recent advances in fluorescent materials for fluorescence molecular imaging: a review.RSC advances · 2025Review
- An insight into the role of ESIPT/TICT-based antioxidant flavone analogues in fluoro-probing diabetes-induced viscosity changes: a unified experimental and theoretical endeavour.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Fluorescent Nanodiamonds for High-Resolution Thermometry in Biology.Nanomaterials (Basel, Switzerland) · 2024Review
- Synthesis of BODIPY-pyrrolo[3,4-Frontiers in chemistry · 2024Article
- Unraveling the photophysical characteristics and biological applications of vinyl sulfones as viscosity sensors.RSC advances · 2023Article
- Investigation of apoptosis based on fluorescence lifetime imaging microscopy with a mitochondria-targeted viscosity probe.RSC advances · 2021Article
- Exploring NIR Aza-BODIPY-Based Polarity Sensitive Probes with ON-and-OFF Fluorescence Switching in Pluronic Nanoparticles.Polymers · 2020Article
- Effect of the Substitution Position on the Electronic and Solvatochromic Properties of Isocyanoaminonaphthalene (ICAN) Fluorophores.Molecules (Basel, Switzerland) · 2019Article
- A Threshold-Limited Fluorescence Probe for Viscosity.Frontiers in chemistry · 2019Article
- Targeted fluorescence lifetime probes reveal responsive organelle viscosity and membrane fluidity.PloS one · 2019Article
- Simultaneous Detection of Local Polarizability and Viscosity by a Single Fluorescent Probe in Cells.Biophysical journal · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Intracellular viscosity is a fundamental physical parameter that indicates the functioning of cells. In this work, we developed a simple boron-dipyrromethene (BODIPY)-based probe, BTV, for cellular mitochondria viscosity imaging by coupling a simple BODIPY rotor with a mitochondria-targeting unit. The BTV exhibited a significant fluorescence intensity enhancement of more than 100-fold as the solvent viscosity increased. Also, the probe showed a direct linear relationship between the fluorescence lifetime and the media viscosity, which makes it possible to trace the change of the medium viscosity. Furthermore, it was demonstrated that BTV could achieve practical applicability in the monitoring of mitochondrial viscosity changes in live cells through fluorescence lifetime imaging microscopy (FLIM).
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