Evidence map›Paper›PMID 27589703›Full record

ReviewMolecules (Basel, Switzerland)2016

Stereoselective Synthesis of α-Amino-C-phosphinic Acids and Derivatives.

José Luis Viveros-Ceballos, Mario Ordóñez, Francisco J Sayago, Carlos Cativiela

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Synthesis of Amino-Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. OrganophosphorusFrontiers in chemistry · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Plausible Pnicogen Bonding ofFrontiers in chemistry · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

José Luis Viveros-CeballosSecretaría Académica, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209 Cuernavaca, Morelos, Mexico. jlvc@uaem.mx.
Mario OrdóñezCentro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209 Cuernavaca, Morelos, Mexico. palacios@uaem.mx.
Francisco J SayagoDepartamento de Química Orgánica, Universidad de Zaragoza-CSIC, ISQCH, 50009 Zaragoza, Spain. jsayago@unizar.es.
Carlos CativielaDepartamento de Química Orgánica, Universidad de Zaragoza-CSIC, ISQCH, 50009 Zaragoza, Spain. cativiela@unizar.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Amino-C-phosphinic acids and derivatives are an important group of compounds of synthetic and medicinal interest and particular attention has been dedicated to their stereoselective synthesis in recent years. Among these, phosphinic pseudopeptides have acquired pharmacological importance in influencing physiologic and pathologic processes, primarily acting as inhibitors for proteolytic enzymes where molecular stereochemistry has proven to be critical. This review summarizes the latest developments in the asymmetric synthesis of acyclic and phosphacyclic α-amino-C-phosphinic acids and derivatives, following in the first case an order according to the strategy used, whereas for cyclic compounds the nitrogen embedding in the heterocyclic core is considered. In addition selected examples of pharmacological implications of title compounds are also disclosed.

Indexed as

Amino AcidsPhosphinic AcidsAmino AcidsPhosphinic Acidsbiological activitystereoselective synthesisα-amino acidsα-amino-C-phosphinatesα-amino-C-phosphinic acids

Identifiers

PMID27589703
PMCPMC6274224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.