ArticleMolecules (Basel, Switzerland)2016
Dimacrolide Sesquiterpene Pyridine Alkaloids from the Stems of Tripterygium regelii.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Structure Characterization of Four New Sesquiterpene Pyridine Alkaloids fromMolecules (Basel, Switzerland) · 2024Article
- Natural Nitrogenous Sesquiterpenoids and Their Bioactivity: A Review.Molecules (Basel, Switzerland) · 2020Review
- Macrolide sesquiterpene pyridine alkaloids from the stems of Tripterygium regelii.Journal of natural medicines · 2019Article
- New Abietane and Kaurane Type Diterpenoids from the Stems of Tripterygium regelii.International journal of molecular sciences · 2017Article
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Authors and funding
5 authors.
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Abstract
Two new dimacrolide sesquiterpene pyridine alkaloids (DMSPAs), dimacroregelines A (1) and B (2), were isolated from the stems of Tripterygium regelii. The structures of both compounds were characterized by extensive 1D and 2D NMR spectroscopic analyses, as well as HRESIMS data. Compounds 1 and 2 are two rare DMSPAs possessing unique 2-(3'-carboxybutyl)-3-furanoic acid units forming the second macrocyclic ring, representing the first example of DMSPAs bearing an extra furan ring in their second macrocyclic ring system. Compound 2 showed inhibitory effects on the proliferation of human rheumatoid arthritis synovial fibroblast cell (MH7A) at a concentration of 20 μM.
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