ArticleProceedings of the National Academy of Sciences of the United States of America2016
Pairwise interactions and the battle against combinatorics in multidrug therapies.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- A Novel Approach to Zero-Shot Drug-Drug Interaction Prediction Enabled by EHR-Augmented Knowledge Graphs.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Optimizing drug combinations to resurrect the potency of failed antibody therapy against emerging COVID-19 variants using IDentif.AI.Frontiers in digital health · 2026Article
- Interactions within higher-order antibiotic combinations do not influence the rate of adaptation in bacteria.Evolution; international journal of organic evolution · 2025Article
- Automated and miniaturized screening of antibiotic combinationsActa pharmaceutica Sinica. B · 2024Article
- Mutators can drive the evolution of multi-resistance to antibiotics.PLoS genetics · 2023Article
- Sample-efficient identification of high-dimensional antibiotic synergy with a normalized diagonal sampling design.PLoS computational biology · 2022Article
- Uncovering Key Metabolic Determinants of the Drug Interactions Between Trimethoprim and Erythromycin inFrontiers in microbiology · 2021Article
- Multiobjective optimization identifies cancer-selective combination therapies.PLoS computational biology · 2020Article
- Moonshots for aging.Nutrition and healthy aging · 2020Review
- Allosteric inhibition explained through conformational ensembles sampling distinct "mixed" states.Computational and structural biotechnology journal · 2020Review
- Guided screen for synergistic three-drug combinations.PloS one · 2020Article
- Design of high-order antibiotic combinations against M. tuberculosis by ranking and exclusion.Scientific reports · 2019Article
- Diagonal Method to Measure Synergy Among Any Number of Drugs.Journal of visualized experiments : JoVE · 2018Article
- Prevalence and patterns of higher-order drug interactions inNPJ systems biology and applications · 2018Article
- Suppressive drug combinations and their potential to combat antibiotic resistance.The Journal of antibiotics · 2017Review
- Article
- Efficient measurement and factorization of high-order drug interactions inScience advances · 2017Article
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1 author.
Funding
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.