ArticleJCI insight2016
Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.
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Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 167 papers, 2 of them syntheses that pooled it.
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167citing papers in PubMed, 2 pooled it
19.8field-weighted citation impact, top 1% of its field
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Who cites it
167 citing papers in PubMed, 2 syntheses or guidelines pooled it, 296 citations in OpenAlex.
- Insights into the Genetic and Epigenetic Landscape of Endocrine Autoimmunity: A Systematic Review.Genes · 2025Pooled it
- Prevalence of Ophthalmological Manifestations in Patients with Inborn Errors of Immunity: A Systematic Review and Meta-Analysis.Journal of clinical immunology · 2025Pooled it
- Efficacy of Cochleated Amphotericin B in Mouse and Human Mucocutaneous Candidiasis.Antimicrobial agents and chemotherapy · 2022Trial
- SARS-CoV-2 Spike Protein-Directed Monoclonal Antibodies May Ameliorate COVID-19 Complications in APECED Patients.Frontiers in immunology · 2021Trial
- Trial
- Ultrarapid Measurement of Diagnostic Antibodies by Magnetic Capture of Immune Complexes.Scientific reports · 2017Trial
- Approach to the patient with APS-1/APECED.The Journal of clinical endocrinology and metabolism · 2026Article
- IFN-γ-producing self-reactive CD4+ T cells induce autoimmune adrenalitis in a mouse model of Addison's disease.JCI insight · 2026Article
- Interface between inborn errors of immunity and rheumatological disorders in children: A pediatrician's conundrum.World journal of clinical pediatrics · 2026Review
- Clinical, genetic, and immunologic features of APS-1 patients from the Middle East, and a review of the literature.Journal of human immunity · 2026Article
- Ruxolitinib prevents irreversible autoimmune endocrinopathies in APECED.Nature communications · 2026Article
- Performance of expanded diagnostic criteria for APECED in independent cohorts and implications for earlier diagnosis.JCI insight · 2026Article
- Hidden battles: dissecting host-fungal interactions and immune heterogeneity in infection outcomes.mSphere · 2026Review
- Long-term follow-up of autoimmune polyendocrine syndrome type 1 in Norway.The Journal of clinical endocrinology and metabolism · 2026Article
- Limited penetrance of dominantly inherited AIRE variants in a population-based cohort.Human molecular genetics · 2026Article
- Selective JAK Inhibition Reveals Paradoxical and Hierarchical Control of interferon-γ-driven Autoimmunity in AIRE Deficiency.bioRxiv : the preprint server for biology · 2026Article
- A Novel Autoimmune Presentation of Wiskott-Aldrich Syndrome: Type 1 Diabetes.Immunity, inflammation and disease · 2026Article
- Article
- Intravenous Glucose Tolerance Tests in Predicting Diabetes Onset in APECED: A Retrospective Cohort Study.Journal of the Endocrine Society · 2026Article
- Article
107 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
44 authors at 8 institutions in 1 country.
Elise M N FerreFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Stacey R RoseFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Sergio D RosenzweigImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Peter D BurbeloDental Clinical Research Core, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA.
Kimberly R RomitoImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Julie E NiemelaImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Lindsey B RosenImmunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Timothy J BreakFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Wenjuan GuClinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., National Cancer Institute (NCI) Campus at Frederick, Frederick, Maryland, USA.
Sally HunsbergerBiostatistics Research Branch, Division of Clinical Research, NIAID, NIH, Bethesda, Maryland, USA.
Sarah K BrowneImmunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Amy P HsuImmunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Shakuntala RampertaapImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Muthulekha SwamydasFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Amanda L CollarFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Heidi H KongDermatology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, USA.
Chyi-Chia Richard LeeLaboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, USA.
David ChascsaTranslational Hepatology Unit, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Thomas SimcoxTranslational Hepatology Unit, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Angela PhamFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Anamaria BondiciFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Mukil NatarajanFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Joseph MonsaleImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
David E KleinerDermatology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, USA.
Martha QuezadoDermatology Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, USA.
Ilias AlevizosSjögren's Syndrome and Salivary Gland Dysfunction Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA.
Niki M MoutsopoulosOral Immunity and Inflammation Unit, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA.
Lynne YockeyFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA; Immunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Cathleen FreinClinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., National Cancer Institute (NCI) Campus at Frederick, Frederick, Maryland, USA.
Ariane SoldatosUndiagnosed Diseases Program, Common Fund, NIH Office of the Director and National Human Genome Research Institute, Bethesda, Maryland, USA.
Katherine R CalvoHematology Section, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Jennifer AdjemianEpidemiology Unit, Laboratory of Clinical Infectious Diseases, NIH, Bethesda, Maryland, USA.
Morgan N SimilukLaboratory of Immunology, NIAID, NIH, Bethesda, Maryland, USA.
David M LangPediatric Consult Service, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Kelly D StoneLaboratory of Allergic Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Gulbu UzelImmunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Jeffrey B KoppKidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Rachel J BishopConsult Services Section, National Eye Institute, NIH, Bethesda, Maryland, USA.
Steven M HollandImmunopathogenesis Section, Laboratory of Clinical Infectious Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Kenneth N OlivierCardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA.
Thomas A FleisherImmunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, Maryland, USA.
Theo HellerTranslational Hepatology Unit, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA.
Karen K WinerPediatric Growth and Nutrition Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.
Michail S LionakisFungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health Clinical Center · USCenter for Cancer Research · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Eye Institute · USNational Heart Lung and Blood Institute · USNational Institute of Dental and Craniofacial Research · USNational Institutes of Health · US
Funding
Studies of Inherited Causes of Fungal SusceptabilityZIAAI001122 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROSENZWEIG, SERGIO · 2010 to 2025
$26.0MImmunopathogenesis of Fungal InfectionsZIAAI001175 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LIONAKIS, MICHAIL · 2012 to 2025
$23.9MClinical Investigations of Sjogren's SyndromeZIADE000704 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI WARNER, BLAKE · 2009 to 2025
$22.3MEffects of systemic and topical perturbations on human microbesZIABC011558 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KONG, HEIDI · 2014 to 2021
$6.9MInvestigation of non-cirrhotic portal hypertension.ZIADK075008 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI HELLER, THEO · 2009 to 2025
$4.5MInflammatory and immune dysregulation associated lung diseaseZIAHL006201 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI OLIVIER, KENNETH · 2015 to 2022
$2.1MMutation Analysis Of Selected Lymphoid Immune DisordersZIACL010304 · CLC · CLINICAL CENTER · PI ROSENZWEIG, SERGIO · 2009 to 2025
$0kCCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
Abstract
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare primary immunodeficiency disorder typically caused by homozygous
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