ReviewJournal of Raman spectroscopy : JRS2016
Achieving optimal SERS through enhanced experimental design.
Review in Journal of Raman spectroscopy : JRS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Gold Nanoparticles in Prostate Cancer: Advances in Targeted Therapy, Diagnostics, and Precision Nanomedicine.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Surface-Enhanced Raman Spectroscopy (SERS) Based Biological and Environmental 2D and 3D Imaging.ACS environmental Au · 2025Review
- Detection and quantification of ergothioneine in human serum using surface enhanced Raman scattering (SERS).The Analyst · 2025Article
- The Optimized Preparation Conditions of Cellulose Triacetate Hollow Fiber Reverse Osmosis Membrane with Response Surface Methodology.Polymers · 2023Article
- Recent Advances in the Use of Surface-Enhanced Raman Scattering for Illicit Drug Detection.Sensors (Basel, Switzerland) · 2022Review
- Discriminative and quantitative analysis of norepinephrine and epinephrine by surface-enhanced Raman spectroscopy with gold nanoparticle suspensions.Analytical and bioanalytical chemistry · 2022Article
- SERRS Detection on Silver Nanoparticles Supported on Acid-Treated Melamine-Resin Microspheres.Nanomaterials (Basel, Switzerland) · 2021Article
- Surface Enhanced Raman Spectroscopy for Quantitative Analysis: Results of a Large-Scale European Multi-Instrument Interlaboratory Study.Analytical chemistry · 2020Article
- Doped N/Ag Carbon Dot Catalytic Amplification SERS Strategy for Acetamiprid Coupled Aptamer with 3,3'-Dimethylbiphenyl-4,4'-diamine Oxidizing Reaction.Nanomaterials (Basel, Switzerland) · 2019Article
- Three-Dimensional Hierarchical Reticular Nanostructure ofNanomaterials (Basel, Switzerland) · 2018Article
- Rapid Detection of Bacteria from Blood with Surface-Enhanced Raman Spectroscopy.Analytical chemistry · 2016Article
- Achieving optimal SERS through enhanced experimental design.Journal of Raman spectroscopy : JRS · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
One of the current limitations surrounding surface-enhanced Raman scattering (SERS) is the perceived lack of reproducibility. SERS is indeed challenging, and for analyte detection, it is vital that the analyte interacts with the metal surface. However, as this is analyte dependent, there is not a single set of SERS conditions that are universal. This means that experimental optimisation for optimum SERS response is vital. Most researchers optimise one factor at a time, where a single parameter is altered first before going onto optimise the next. This is a very inefficient way of searching the experimental landscape. In this review, we explore the use of more powerful multivariate approaches to SERS experimental optimisation based on design of experiments and evolutionary computational methods. We particularly focus on colloidal-based SERS rather than thin film preparations as a result of their popularity. © 2015 The Authors. Journal of Raman Spectroscopy published by John Wiley & Sons, Ltd.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.