Evidence map›Paper›PMID 27586827›Full record

ReviewThe journal of pain2016

Assessment of Chronic Pain: Domains, Methods, and Mechanisms.

Roger B Fillingim, John D Loeser, Ralf Baron, Robert R Edwards

Registry-linked trialAbstract readReview
In one paragraph

Review in The journal of pain, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06030297 (Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.), which is not on this map. Cited by 179 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06030297 nacompletednot on this mapstarted 2023, after this paper: background citation

Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.

TypeinterventionalSponsorUniversity of UtahRan2023 to 2026Enrolled75ConditionsPeripheral NeuropathyArmsDiode Laser fiber type Selective Stimulator, ZTlido 1.8 % Topical System, PeriCam PSI NR, Medoc Quantitative Sensory Testing, Inactive Topical System
3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  8. Multidimensional Pain Assessment Tools for Ambulatory and Inpatient Nursing Practice.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2020
    Pooled it
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  11. An exploration of the relationship between perceived injustice and pain severity in breast cancer survivors: a structural equation model.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roger B FillingimPain Research & Intervention Center of Excellence, University of Florida, Gainesville, Florida. Electronic address: rfilling@ufl.edu.
John D LoeserUniversity of Washington, Department of Neurological Surgery, Seattle, Washington.
Ralf BaronUniversity of Kiel, Department of Neurology, Kiel, Germany.
Robert R EdwardsHarvard Medical School, Boston, Massachusetts.

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Karyn A Esser, Todd Manini · 2007 to 2026
$22.8M
Pain and Aging Research Translational InitiativeK07AG046371 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2014 to 2018
$667k
NIA NIH HHS K07 AG046371NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

unlabelledAccurate classification of chronic pain conditions requires reliable and valid pain assessment. Moreover, pain assessment serves several additional functions, including documenting the severity of the pain condition, tracking the longitudinal course of pain, and providing mechanistic information. Thorough pain assessment must address multiple domains of pain, including the sensory and affective qualities of pain, temporal dimensions of pain, and the location and bodily distribution of pain. Where possible, pain assessment should also incorporate methods to identify pathophysiological mechanisms underlying the pain. This article discusses assessment of chronic pain, including approaches available for assessing multiple pain domains and for addressing pathophysiological mechanisms. We conclude with recommendations for optimal pain assessment. PERSPECTIVE: Pain assessment is a critical prerequisite for accurate pain classification. This article describes important features of pain that should be assessed, and discusses methods that can be used to assess the features and identify pathophysiological mechanisms contributing to pain.

Indexed as

Chronic PainElectronicsHumansPain MeasurementPain Thresholdneuropathic painPain assessmentpain intensitypain mechanismsquantitative sensory testing

Identifiers

PMID27586827
PMCPMC5010652

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.