Evidence map›Paper›PMID 27586815›Full record

ReviewActa neurologica Scandinavica2017

Alcohol withdrawal syndrome: mechanisms, manifestations, and management.

S Jesse, G Bråthen, M Ferrara, M Keindl, E Ben-Menachem, R Tanasescu, E Brodtkorb, M Hillbom, M A Leone, A C Ludolph

Abstract readReview
In one paragraph

Review in Acta neurologica Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Baclofen for alcohol withdrawal.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Trial
  8. Observational
  9. Article
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  16. Biochemistry and biophysics reports · 2026
    Article
  17. Acid accumulation in bipolar disorder.Journal of affective disorders · 2026
    Article
  18. Article
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

S JesseDepartment of Neurology, University Ulm, Ulm, Germany.
G BråthenDepartment of Neurology and Clinical Neurophysiology, Trondheim University Hospital, Trondheim, Norway.
M FerraraUnit of Neurology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
M KeindlDanube University Krems, Krems, Austria.
E Ben-MenachemInstitute of Clinical Neuroscience and Neurophysiology, SU/Sahlgrenska Hospital, Gothenburg, Sweden.
R TanasescuDepartment of Neurology, Neurosurgery and Psychiatry, University of Medicine and Pharmacy Carol Davila, Colentina Hospital, Bucharest, Romania.
E BrodtkorbDepartment of Neurology and Clinical Neurophysiology, Trondheim University Hospital, Trondheim, Norway.
M HillbomDepartment of Neurology, Oulu University Hospital, Oulu, Finland.
M A LeoneUnit of Neurology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
A C LudolphDepartment of Neurology, University Ulm, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alcohol withdrawal syndrome is a well-known condition occurring after intentional or unintentional abrupt cessation of heavy/constant drinking in patients suffering from alcohol use disorders (AUDs). AUDs are common in neurological departments with patients admitted for coma, epileptic seizures, dementia, polyneuropathy, and gait disturbances. Nonetheless, diagnosis and treatment are often delayed until dramatic symptoms occur. The purpose of this review is to increase the awareness of the early clinical manifestations of AWS and the appropriate identification and management of this important condition in a neurological setting.

Indexed as

Alcohol Withdrawal DeliriumAlcohol Withdrawal SeizuresBiomarkersHumansBiomarkersalcohol withdrawalclinical managementdelirium tremensepileptic seizurestherapy

Identifiers

PMID27586815
PMCPMC6084325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.