Evidence map›Paper›PMID 27586671›Full record

ArticleInternational ophthalmology2017

Postoperative endophthalmitis incidence after intravitreal therapy: a comparison of two different preoperative antibiotic prophylaxis.

Sergio Piscitello, Maria Vadalà

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sergio PiscitelloDipartimento di Biomedicina sperimentale e Neuroscience Cliniche, University of Palermo, c/o U.O.C. Oculistica, Policlinico Paolo Giaccone, via del Vespro 129, 90127, Palermo, Italy.
Maria VadalàDipartimento di Biomedicina sperimentale e Neuroscience Cliniche, University of Palermo, c/o U.O.C. Oculistica, Policlinico Paolo Giaccone, via del Vespro 129, 90127, Palermo, Italy. maria.vadala@unipa.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevention of postoperative endophthalmitis (POE) is a goal of every ophthalmic procedure and also in intravitreal therapy (IVT). This comparative retrospective study targets whether systemic and topical preoperative antibiotic prophylaxis (PAP) regimen does prevent POE after IVT in a higher rate compared with topical PAP alone. Out of 6111 IVT performed over a period of 103.5 months, in the study group A patients were treated with systemic and topical PAP (2881 IVT), and in the study group B patients were treated only with topical PAP (3230 IVT). Intravitreal drugs were anti-VEGF, triamcinolone and dexamethasone implants. The incidence of POE in group A (1/2881 or 0.035 % per injection) was not significantly different (P = 0.4) from that in suite B (1/3230 or 0.031 % per injection). Our study states that systemic PAP does not modify the risk of postoperative endophthalmitis in patients treated with IVT.

Indexed as

AgedAged, 80 and overAngiogenesis InhibitorsAnti-Bacterial AgentsAntibiotic ProphylaxisDexamethasoneDose-Response Relationship, DrugDrug ImplantsEndophthalmitisFemaleGlucocorticoidsHumansIncidenceIntravitreal InjectionsMaleMiddle AgedAngiogenesis InhibitorsAnti-Bacterial AgentsDexamethasoneDrug ImplantsGlucocorticoidsTriamcinolone AcetonideVascular Endothelial Growth Factor AAntibiotic prophylaxisEndophthalmitisIncidenceIntravitreal therapy

Identifiers

PMID27586671

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.