ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2016
Bacterial nutrient foraging in a mouse model of enteral nutrient deprivation: insight into the gut origin of sepsis.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review).Molecular medicine reports · 2026Review
- Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets.Journal of intensive care · 2025Review
- Mouse models for enteral and parenteral nutrition after surgery.Frontiers in veterinary science · 2025Article
- What Is the Role of the Gut in Wound Infections?Advances in surgery · 2023Review
- Impact of Total Parenteral Nutrition on Gut Microbiota in Pediatric Population Suffering Intestinal Disorders.Nutrients · 2022Review
- Re-examining chemically defined liquid diets through the lens of the microbiome.Nature reviews. Gastroenterology & hepatology · 2021Review
- Why is it worth remembering the lung microbiome in ICU patients?Anaesthesiology intensive therapy · 2021Review
- Analysis of Intestinal Flora and Levels of Epidermal Growth Factor Receptor, Interleukin-32, and Gastrin 17 in Patients with Gastric Cancer via Carbon Nanoparticle Laparoscopy.BioMed research international · 2021Article
- Gut microbiota in neonates with congenital gastrointestinal surgical conditions: a prospective study.Pediatric research · 2020Article
- New Insights Into Intestinal Failure-Associated Liver Disease in Children.Hepatology (Baltimore, Md.) · 2020Review
- Dietary L-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut.Nature microbiology · 2020Article
- The microbiome and nutrition in critical illness.Current opinion in critical care · 2019Review
- Generation ofACS infectious diseases · 2019Article
- Probiotic research in neonates with congenital gastrointestinal surgical conditions - Now is the time.Microbial biotechnology · 2019Article
- Stable-Isotope Probing of Human and Animal Microbiome Function.Trends in microbiology · 2018Review
- Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin.Translational research : the journal of laboratory and clinical medicine · 2017Review
- Gastrointestinal immune and microbiome changes during parenteral nutrition.American journal of physiology. Gastrointestinal and liver physiology · 2017Review
- Hypermetabolism and Nutritional Support in Sepsis.Surgical infectionsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
Total parenteral nutrition (TPN) leads to a shift in small intestinal microbiota with a characteristic dominance of Proteobacteria This study examined how metabolomic changes within the small bowel support an altered microbial community in enterally deprived mice. C57BL/6 mice were given TPN or enteral chow. Metabolomic analysis of jejunal contents was performed by liquid chromatography/mass spectrometry (LC/MS). In some experiments, leucine in TPN was partly substituted with [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.