ArticleChinese journal of integrative medicine2017
Changes in small intestinal motility and related hormones by acupuncture stimulation at Zusanli (ST 36) in mice.
Article in Chinese journal of integrative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Effects of transcutaneous electrical acupoint stimulation on early postoperative pain and recovery: a comprehensive systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2024Pooled it
- Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Efficacy and safety of acupuncture in post-stroke constipation: a systematic review and meta-analysis.Frontiers in neuroscience · 2023Pooled it
- Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Nutrition and Promotes Early Recovery of Gastrointestinal Function in Patients with Colorectal Cancer.Combinatorial chemistry & high throughput screening · 2025Trial
- Acupuncture Combined with Early Enteral Nutrition on Patients with Postoperative Laparoscopic Common Bile Duct Exploration: A Prospective Randomized Trial.Chinese journal of integrative medicine · 2020Trial
- Efficacy of Electro-acupuncture in Treatment of Functional Constipation: A Randomized Controlled Trial.Current medical science · 2020Trial
- Effect of an Integrated Early Enteral Nutrition Management Protocol on Nutritional Target Attainment in Mechanically Ventilated ICU Patients: A Quasi-Experimental Study Guided by the MRC Framework.Nursing in critical care · 2026Article
- Research Progress of Acupuncture in Disease Management through Autonomic Nerve System Modulation.Chinese journal of integrative medicine · 2025Review
- The Autonomic Nervous System in Acupuncture for Gastrointestinal Dysmotility: From Anatomical Insights to Clinical Medicine.International journal of medical sciences · 2025Review
- Acupuncture and moxibustion intervention in functional dyspepsia: Gastric and duodenal regulation.Heliyon · 2024Review
- Effect of acupuncture therapy for postoperative gastrointestinal dysfunction in gastric and colorectal cancers: an umbrella review.Frontiers in oncology · 2024Review
- Acupuncture for Parkinson's disease-related constipation: current evidence and perspectives.Frontiers in neurology · 2023Article
- Development of a Simple Single-Acupoint Electroacupuncture Frame and Evaluation of the Acupuncture Effect in Rabbits.Veterinary sciences · 2021Article
- An Apriori Algorithm-Based Association Rule Analysis to Identify Acupoint Combinations for Treating Diabetic Gastroparesis.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Acupuncture therapy protects PCOS patients with diabetes by regulating miR-32-3p/PLA2G4A pathway.American journal of translational research · 2021Article
- Neuromechanism of acupuncture regulating gastrointestinal motility.World journal of gastroenterology · 2020Review
- Effect of Catgut Embedment in Du Meridian Acupoint on Mental and Psychological Conditions of Patients with Gastroesophageal Reflux Disease.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Article
- MicroRNA in Acupuncture Studies: Does Small RNA Shed Light on the Biological Mechanism of Acupuncture?Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Electroacupuncture at LI11 promotes jejunal motility via the parasympathetic pathway.BMC complementary and alternative medicine · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo clarify the effects of acupuncture stimulation at Zusanli (ST 36) on the hormonal changes.
methodsEight-week-old male C57BL/6 mice received acupuncture stimulation at acupoint ST 36 or Quchi (LI 11) once a day for 3 or 5 days in the acupuncture-stimulated groups, but not received in the normal group (n=6 in each group). On day 3 or 5, animals were given 0.1 mL of charcoal orally with a bulbed steel needle, 30 min after the last acupuncture stimulation. Ten minutes later, mice were anesthetized, and the intestinal transit and the concentrations of vasoactive intestinal peptide (VIP), motilin, ghrelin and gastrin in the serum were measured.
resultsCompared to no acupuncture stimulation, acupuncture stimulation at ST 36 for 5 days increased the intestinal transit and down-regulated the concentration of VIP and up-regulated the concentrations of motilin, ghrelin and gastrin (P<0.05 or 0.01), whereas acupuncture stimulation at LI 11 did not change them signifificantly (P>0.05).
conclusionAcupuncture stimulation at ST 36 for 5 days enhances the small intestinal motility and regulates the secretion of hormones related to small intestinal motility.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.