Evidence map›Paper›PMID 27586465›Full record

ArticleJournal of veterinary science2017

Inoculation of Lewis lung carcinoma cells enhances formalin-induced pain behavior and spinal Fos expression in mice.

Jae-Gyun Choi, Jae-Min Kim, Dong-Wook Kang, Jung-Wan Choi, Jin Bong Park, Seong-Hun Ahn, Yeonhee Ryu, Hyun-Woo Kim

Abstract read
In one paragraph

Article in Journal of veterinary science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Pharmacokinetic, Hemostatic, and Anticancer Properties of a Low-Anticoagulant Bovine Heparin.TH open : companion journal to thrombosis and haemostasis · 2022
    Article
  3. NFAT5 Deficiency Alleviates Formalin-Induced Inflammatory Pain Through mTOR.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jae-Gyun ChoiDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Jae-Min KimDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Dong-Wook KangDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Jung-Wan ChoiDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Jin Bong ParkDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.
Seong-Hun AhnDepartment of Meridian & Acupoint, College of Oriental Medicine, Wonkwang University, Iksan 54538, Korea.
Yeonhee RyuKM Fundamental Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Hyun-Woo KimDepartment of Physiology and Medical Science and Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Korea.

Funding

NIEHS NIH HHS 27398C0007
6 · The paper itself

Abstract

The incidence of lung cancer has rapidly increased and cancer patients at a later cancer stage frequently suffer from unbearable cancer-associated pain. However, the pathophysiology of lung cancer pain has not been fully described due to a lack of appropriate animal models. This study was designed to determine the effect of Lewis lung carcinoma (LLC) cell inoculation on formalin-induced pain behavior and spinal Fos expression in C57BL/6 mice. LLC cells (1.5 × 10

Indexed as

Analgesics, Non-NarcoticAnimalsCancer PainCarcinoma, Lewis LungFormaldehydeIbuprofenMaleMiceMice, Inbred C57BLNeoplasm TransplantationOncogene Proteins v-fosPainSpinal CordSpinal Cord Dorsal HornAnalgesics, Non-NarcoticFormaldehydeIbuprofenOncogene Proteins v-fosformalinFosLewis lung carcinomalung neoplasmspain

Identifiers

PMID27586465
PMCPMC5639078

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.