ArticleEpidemiology and infection2016
Colistin-resistant Escherichia coli clinical isolate harbouring the mcr-1 gene in Ecuador.
Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 69 citations in OpenAlex.
- Genomic Insights into Colistin and Tigecycline Resistance in ESBL-ProducingAntibiotics (Basel, Switzerland) · 2025Article
- Detection of mobile colistin resistance genesMicrobiology resource announcements · 2024Article
- Molecular epidemiology of carbapenem-resistant gram-negative bacilli in Ecuador.BMC infectious diseases · 2024Article
- Detection of Plasmid-Mediated Resistance against Colistin in Multi-Drug-Resistant Gram-Negative Bacilli Isolated from a Tertiary Hospital.Microorganisms · 2023Article
- Risk factors associated with colistin resistance in carbapenemase-producing Enterobacterales: a multicenter study from a low-income country.Annals of clinical microbiology and antimicrobials · 2023Article
- Mobile Colistin Resistance (Antibiotics (Basel, Switzerland) · 2023Review
- Colistin resistance inRevista panamericana de salud publica = Pan American journal of public health · 2023Article
- Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis.FEMS microbiology reviews · 2022Review
- Epidemiology ofFrontiers in microbiology · 2022Article
- An Update of Mobile Colistin Resistance in Non-Fermentative Gram-Negative Bacilli.Frontiers in cellular and infection microbiology · 2022Review
- Approaches for characterizing and tracking hospital-associated multidrug-resistant bacteria.Cellular and molecular life sciences : CMLS · 2021Review
- Broiler Farms and Carcasses Are an Important Reservoir of Multi-Drug ResistantFrontiers in veterinary science · 2020Article
- Sequencing-based methods and resources to study antimicrobial resistance.Nature reviews. Genetics · 2019Review
- Colistin-resistant Escherichia coli with mcr genes in the livestock of rural small-scale farms in Ecuador.BMC research notes · 2019Article
- The rise and spread ofCritical reviews in microbiology · 2019Review
- Characterization of cefotaxime resistant Escherichia coli isolated from broiler farms in Ecuador.PloS one · 2019Article
- Article
- High prevalence of carriage ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Prevalence and Characterization of Multi-Drug-Resistant Gram-Negative Bacilli Isolated From Lebanese Poultry: A Nationwide Study.Frontiers in microbiology · 2018Article
- Genomic and Molecular Characterization of Clinical Isolates of Enterobacteriaceae HarboringAntimicrobial agents and chemotherapy · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colistin resistance mediated by the mcr-1 gene has been reported worldwide, but to date not from the Andean region, South America. We report the first clinical isolate of Escherichia coli harbouring the mcr-1 gene in Ecuador. The strain was isolated from peritoneal fluid from a 14-year-old male with acute appendicitis, and subjected to molecular analysis. The minimum inhibitory concentration of colistin for the strain was 8 mg/ml and it was susceptible to carbapenems but resistant to tigecycline. The strain harboured mcr-1 and bla CTX-M-55 genes and was of sequence type 609. The recognition of an apparently commensal strain of E. coli harbouring mcr-1 serves as an alert to the presence in the region of this recently described resistance mechanism to one of the last line of drugs available for the treatment of multi-resistant Gram-negative infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.