Evidence map›Paper›PMID 27586200›Full record

ArticleBMC oral health2016

Association between maximum occlusal force and 3-year all-cause mortality in community-dwelling elderly people.

Toshimitsu Iinuma, Yasumichi Arai, Michiyo Takayama, Yukiko Abe, Tomoka Ito, Yugaku Kondo, Nobuyoshi Hirose, Nobuhito Gionhaku

Abstract read
In one paragraph

Article in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Toshimitsu IinumaDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan. iinuma.toshimitsu@nihon-u.ac.jp.ORCID http://orcid.org/0000-0001-7705-5550
Yasumichi AraiCenter for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
Michiyo TakayamaCenter for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan.
Yukiko AbeCenter for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
Tomoka ItoDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Yugaku KondoDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Nobuyoshi HiroseCenter for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
Nobuhito GionhakuDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong the very elderly, poor oral health reduces life expectancy. In this study, differences in the magnitude of the maximum occlusal force (MOF) in the very elderly were examined in terms of effects on all-cause mortality in a 3-year follow-up.

methodsWe evaluated 489 community-living elderly individuals aged 85 years or older. MOF was measured using an occlusal force measuring device, and participants were classified into three groups according to gender- and dental status-sensitive tertiles. Demographic variables, cognitive, physical function, psychological status, oral health, comorbidity, and blood chemistry factors were assessed. One-way analyses of variance, χ (2) tests, and the Kruskal-Wallis test were used for statistical analyses. The relationship between MOF tertiles and 3-year all-cause mortality was examined using a multivariate Cox model analysis after adjusting for confounding factors.

resultsMOF tertiles were significantly associated with cognitive impairment, number of teeth, limitations on chewable foods, handgrip strength, timed up-and-go test, and diabetes mellitus. During the follow-up period, 74 subjects died. Subjects with the highest MOF had a significantly lower mortality rate than other groups (log rank P  =  0.031). In the univariate Cox model, MOF tertiles were independently associated with a lower risk of death (HR = 0.69, 95 % CI = 0.51-0.91). Even after adjusting for various confounders in the multivariate Cox model (Model 1), MOF was independently associated with a lower risk of death (HR = 0.67, 95 % CI = 0.50-0.91). In model 2, we added handgrip strength as a confounder and found that the HR for MOF was attenuated (HR = 0.73, 95 % CI = 0.54-0.99), but still statistically significant.

conclusionsIn a cohort of the very elderly, MOF was independently associated with all-cause mortality after adjusting for various health issues. Moreover, this independent association remained after a further adjustment for handgrip strength; however, the HR was attenuated. This suggests that MOF and handgrip strength may share a common mechanism of a general decrease in muscle strength, possibly sarcopenia, which is a significant cause of mortality in the very old.

Indexed as

Bite ForceHand StrengthIndependent LivingMortalityAged, 80 and overComorbidityFemaleHumansMaleProspective StudiesAll-cause mortalityBite forceHealthy life expectancyVery elderly people

Identifiers

PMID27586200
PMCPMC5009498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.