ReviewThe Science of the total environment2016
Recent advances in simultaneous analysis of bisphenol A and its conjugates in human matrices: Exposure biomarker perspectives.
Review in The Science of the total environment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Canned food intake and urinary bisphenol a concentrations: a randomized crossover intervention study.Environmental science and pollution research international · 2019Trial
- Emerging evidence for skeletal muscle as a target of BPA exposure.BMC endocrine disorders · 2026Review
- The cannabinoid receptor 2 is an in vivo receptor of bisphenol A during bone formation.Journal of hazardous materials · 2026Article
- Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies-a review of published literature from 2018 to 2023.Archives of toxicology · 2024Review
- A computational assay for identifying millet-derived compounds that antagonize the interaction between bisphenols and estrogen-related receptor gamma.Frontiers in pharmacology · 2024Article
- The Carcinogenic Potential of Bisphenol A in the Liver Based on Transcriptomic Studies.Cancers · 2023Article
- From target analysis to suspect and non-target screening of endocrine-disrupting compounds in human urine.Analytical and bioanalytical chemistry · 2022Article
- Validated single urinary assay designed for exposomic multi-class biomarkers of common environmental exposures.Analytical and bioanalytical chemistry · 2022Article
- Recent advances in analysis of bisphenols and their derivatives in biological matrices.Analytical and bioanalytical chemistry · 2022Review
- Direct LC-MS/MS and indirect GC-MS/MS methods for measuring urinary bisphenol A concentrations are comparable.Environment international · 2021Article
- RepresentativeInternational journal of molecular sciences · 2021Article
- Bisphenol A and Metabolites in Meat and Meat Products: Occurrence, Toxicity, and Recent Development in Analytical Methods.Foods (Basel, Switzerland) · 2021Review
- Pregnancy-specific physiologically-based toxicokinetic models for bisphenol A and bisphenol S.Environment international · 2021Article
- Endocrine disruptors and gut microbiome interactions.Physiological research · 2020Review
- Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease.International journal of molecular sciences · 2020Review
- Toxicokinetics of bisphenol A, bisphenol S, and bisphenol F in a pregnancy sheep model.Chemosphere · 2019Article
- Insights into the effect and interaction mechanism of bisphenol S on lipids hydrolysis in sludge through multi-spectra, thermodynamics, and molecule docking analysis.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Human exposures to bisphenol A (BPA) has attained considerable global health attention and represents one of the leading environmental contaminants with potential adverse health effects including endocrine disruption. Current practice of measuring of exposure to BPA includes the measurement of unconjugated BPA (aglycone) and total (both conjugated and unconjugated) BPA; the difference between the two measurements leads to estimation of conjugated forms. However, the measurement of BPA as the end analyte leads to inaccurate estimates from potential interferences from background sources during sample collection and analysis. BPA glucuronides (BPAG) and sulfates (BPAS) represent better candidates for biomarkers of BPA exposure, since they require in vivo metabolism and are not prone to external contamination. In this work, the primary focus was to review the current state of the art in analytical methods available to quantitate BPA conjugates. The entire analytical procedure for the simultaneous extraction and detection of aglycone BPA and conjugates is covered, from sample pre-treatment, extraction, separation, ionization, and detection. Solid phase extraction coupled with liquid chromatograph and tandem mass spectrometer analysis provides the most sensitive detection and quantification of BPA conjugates. Discussed herein are the applications of BPA conjugates analysis in human exposure assessment studies. Measuring these potential biomarkers of BPA exposure has only recently become analytically feasible and there are limitations and challenges to overcome in biomonitoring studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.