ArticleScientific reports2016
Comprehensive analysis of SET domain gene family in foxtail millet identifies the putative role of SiSET14 in abiotic stress tolerance.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Prevalence of dental caries and associated factors among primary school children in Ethiopia: systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Identification of thePlants (Basel, Switzerland) · 2026Article
- Genome-wide identification and characterization of SET domain family genes in Neopyropia yezoensis.BMC genomics · 2026Article
- Epigenetic Mechanisms Driving Adaptation in Tropical and Subtropical Plants: Insights and Future Directions.Plant, cell & environment · 2025Review
- Article
- Review
- Genome-wide identification and expression analysis of the SET domain-containing gene family in potato (Solanum tuberosum L.).BMC genomics · 2024Article
- Identification of thePlants (Basel, Switzerland) · 2024Article
- Improvement of millets in the post-genomic era.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Review
- Genome-Wide Identification and Characterization of SET Domain Family Genes inInternational journal of molecular sciences · 2022Article
- Multi-omics intervention inFrontiers in plant science · 2022Review
- The function of histone lysine methylation related SET domain group proteins in plants.Protein science : a publication of the Protein Society · 2020Review
- Genome-wide identification and expression profiling of SET DOMAIN GROUP family in Dendrobium catenatum.BMC plant biology · 2020Article
- Adaptation of Foxtail Millet (Frontiers in plant science · 2020Review
- Study on aquaporins of Setaria italica suggests the involvement of SiPIP3;1 and SiSIP1;1 in abiotic stress response.Functional & integrative genomics · 2019Article
- Genome-Wide Characterization of bHLH Genes in Grape and Analysis of their Potential Relevance to Abiotic Stress Tolerance and Secondary Metabolite Biosynthesis.Frontiers in plant science · 2018Article
- Phylogenetic relationship and domain organisation of SET domain proteins of Archaeplastida.BMC plant biology · 2017Article
- Salinity induced differential methylation patterns in contrasting cultivars of foxtail millet (Setaria italica L.).Plant cell reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SET domain-containing genes catalyse histone lysine methylation, which alters chromatin structure and regulates the transcription of genes that are involved in various developmental and physiological processes. The present study identified 53 SET domain-containing genes in C4 panicoid model, foxtail millet (Setaria italica) and the genes were physically mapped onto nine chromosomes. Phylogenetic and structural analyses classified SiSET proteins into five classes (I-V). RNA-seq derived expression profiling showed that SiSET genes were differentially expressed in four tissues namely, leaf, root, stem and spica. Expression analyses using qRT-PCR was performed for 21 SiSET genes under different abiotic stress and hormonal treatments, which showed differential expression of these genes during late phase of stress and hormonal treatments. Significant upregulation of SiSET gene was observed during cold stress, which has been confirmed by over-expressing a candidate gene, SiSET14 in yeast. Interestingly, hypermethylation was observed in gene body of highly differentially expressed genes, whereas methylation event was completely absent in their transcription start sites. This suggested the occurrence of demethylation events during various abiotic stresses, which enhance the gene expression. Altogether, the present study would serve as a base for further functional characterization of SiSET genes towards understanding their molecular roles in conferring stress tolerance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.