ArticleNeurochemical research2016
The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells.
Article in Neurochemical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 54 citations in OpenAlex.
- Modulation of Nrf2/TNF-α and TLR4/TGF-β1 Signaling Pathways by Nigella Sativa Oil and Echinacea Purpurea Extract Attenuates Cyclosporine A-Induced Nephrotoxicity and Immunotoxicity.Cell biochemistry and biophysics · 2026Article
- Thymoquinone as a Multi-Target Modulator of Inflammatory and Immunometabolic Signaling: Mechanisms and Therapeutic Implications.Cell biochemistry and biophysics · 2026Review
- Nigella sativa L. and its bioactive and nutraceutical components in the management of diabetic peripheral neuropathy.Inflammopharmacology · 2024Review
- Cardiovascular Effects of Herbal Products and Their Interaction with Antihypertensive Drugs-Comprehensive Review.International journal of molecular sciences · 2024Review
- Effect ofInternational journal of molecular sciences · 2024Article
- Biochemical Characterization of Ethiopian Black Cumin (International journal of food science · 2024Article
- Comprehensive and updated review on anti-oxidant effects ofIranian journal of basic medical sciences · 2024Review
- RETRACTED: The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer's Disease-like Condition: Mechanistic Insights.Molecules (Basel, Switzerland) · 2023Article
- Antioxidant and Anti-Inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells.International journal of molecular sciences · 2023Article
- In vitro study of Nigella sativa and thymoquinone activity on endothelial activation and monocyte adhesion.Journal of applied biomedicine · 2023Article
- Thymoquinone enhances the antioxidant and anticancer activity of Lebanese propolis.World journal of clinical oncology · 2023Article
- Review
- Article
- Thymoquinone Improved Nonylphenol-Induced Memory Deficit and Neurotoxicity Through Its Antioxidant and Neuroprotective Effects.Molecular neurobiology · 2022Article
- A new benzaldehyde from the coral-derived fungusJournal of Zhejiang University. Science. B · 2022Article
- Characterization and Antimicrobial Activity ofAntibiotics (Basel, Switzerland) · 2022Article
- Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways.Frontiers in cellular neuroscience · 2022Review
- The Influence of Seasonality on Secondary Metabolite Profiles and Neuroprotective Activities of MossPlants (Basel, Switzerland) · 2022Article
- Protective Effects of Black Cumin (International journal of molecular sciences · 2021Review
- Black Cumin (Nutrients · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Both neuroinflammation and microglial activation are pathological markers of a number of central nervous system (CNS) diseases. During chronic activation of the microglial cells, the induced release of excessive amounts of reactive oxygen species (ROS) and pro-inflammatory cytokines have been implicated in several neurodegenerative diseases such as Alzheimer's disease. Thymoquinone (TQ), a major bioactive compound of the natural product Nigella sativa seed, has been shown to be effective against numerous oxidative stress-induced and inflammatory disorders as well as possess neuroprotective properties. In this study, we investigated the antioxidant effects of TQ on LPS/IFNγ or H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.