Evidence map›Paper›PMID 27585740›Full record

ArticleScientific reports2016

Guidelines to electrode positioning for human and animal electrical impedance myography research.

Benjamin Sanchez, Adam Pacheck, Seward B Rutkove

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
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  10. Modeling and simulation of needle electrical impedance myography in nonhomogeneous isotropic skeletal muscle.IEEE journal of electromagnetics, RF and microwaves in medicine and biology · 2022
    Article
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  18. Electrical impedance myography: A critical review and outlook.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Review
  19. In vivo muscle conduction study of the tongue using a multi-electrode tongue depressor.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin SanchezDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, USA.
Adam PacheckDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, USA.
Seward B RutkoveDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215-5491, USA.

Funding

Innovative Ultrasound Technology in Neuromuscular DiseaseK24NS060951 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI RUTKOVE, SEWARD B. · 2008 to 2017
$1.5M
NINDS NIH HHS K24 NS060951
6 · The paper itself

Abstract

The positioning of electrodes in electrical impedance myography (EIM) is critical for accurately assessing disease progression and effectiveness of treatment. In human and animal trials for neuromuscular disorders, inconsistent electrode positioning adds errors to the muscle impedance. Despite its importance, how the reproducibility of resistance and reactance, the two parameters that define EIM, are affected by changes in electrode positioning remains unknown. In this paper, we present a novel approach founded on biophysical principles to study the reproducibility of resistance and reactance to electrode misplacements. The analytical framework presented allows the user to quantify a priori the effect on the muscle resistance and reactance using only one parameter: the uncertainty placing the electrodes. We also provide quantitative data on the precision needed to position the electrodes and the minimum muscle length needed to achieve a pre-specified EIM reproducibility. The results reported here are confirmed with finite element model simulations and measurements on five healthy subjects. Ultimately, our data can serve as normative values to enhance the reliability of EIM as a biomarker and facilitate comparability of future human and animal studies.

Indexed as

Biomedical ResearchElectric ImpedanceMyographyPractice Guidelines as TopicAdultAnimalsElectrodesHumansMovementMuscle, Skeletal

Identifiers

PMID27585740
PMCPMC5009322

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.