Evidence map›Paper›PMID 27585638›Full record

ArticleScientific reports2016

Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes.

Bipin Kumar Gupta, Satbir Singh, Pawan Kumar, Yean Lee, Garima Kedawat, Tharangattu N Narayanan, Sajna Antony Vithayathil, Liehui Ge, Xiaobo Zhan, Sarika Gupta and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Effect of EuRSC advances · 2025
    Article
  3. Review
  4. Neurotheranostics as personalized medicines.Advanced drug delivery reviews · 2019
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bipin Kumar GuptaLuminescent Materials and Devices Group, Materials Physics and Engineering Division, CSIR- National Physical Laboratory, Dr K S Krishnan Road, New Delhi, 110012, India.
Satbir SinghLuminescent Materials and Devices Group, Materials Physics and Engineering Division, CSIR- National Physical Laboratory, Dr K S Krishnan Road, New Delhi, 110012, India.
Pawan KumarLuminescent Materials and Devices Group, Materials Physics and Engineering Division, CSIR- National Physical Laboratory, Dr K S Krishnan Road, New Delhi, 110012, India.
Yean LeeDepartment of Material Science and Nano Engineering Rice University, Houston, TX 77005, USA.
Garima KedawatDepartment of Physics, Kalindi College, University of Delhi, New Delhi, 110008, India.
Tharangattu N NarayananTIFR- Center for Interdisciplinary sciences, Tata Institute fundamental research, Hydrabad-500075, India.
Sajna Antony VithayathilDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Liehui GeDepartment of Material Science and Nano Engineering Rice University, Houston, TX 77005, USA.
Xiaobo ZhanDepartment of Material Science and Nano Engineering Rice University, Houston, TX 77005, USA.
Sarika GuptaNational Institute of Immunology, Aruna Aseaf Ali Marg, J. N. U. Complex, New Delhi-110067, India.
Angel A MartíDepartment of Chemistry and Bioengineering, Rice University, Houston, Texas 77005, USA.
Robert VajtaiDepartment of Material Science and Nano Engineering Rice University, Houston, TX 77005, USA.
Pulickel M AjayanDepartment of Material Science and Nano Engineering Rice University, Houston, TX 77005, USA.
Benny Abraham KaipparettuDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Funding

Mitochondria-nuclear crosstalk in triple negative breast cancer racial disparityR21CA179720 · NCI · BAYLOR COLLEGE OF MEDICINE · PI KAIPPARETTU, BENNY ABRAHAM · 2013 to 2015
$623k
NCI NIH HHS R21 CA179720
6 · The paper itself

Abstract

Nanoparticles exhibiting both magnetic and luminescent properties are need of the hour for many biological applications. A single compound exhibiting this combination of properties is uncommon. Herein, we report a strategy to synthesize a bifunctional luminomagnetic Gd2-xEuxO3 (x = 0.05 to 0.5) nanorod, with a diameter of ~20 nm and length in ~0.6 μm, using hydrothermal method. Gd2O3:Eu(3+) nanorods have been characterized by studying its structural, optical and magnetic properties. The advantage offered by photoluminescent imaging with Gd2O3:Eu(3+) nanorods is that this ultrafine nanorod material exhibits hypersensitive intense red emission (610 nm) with good brightness (quantum yield more than 90%), which is an essential parameter for high-contrast bioimaging, especially for overcoming auto fluorescent background. The utility of luminomagnetic nanorods for biological applications in high-contrast cell imaging capability and cell toxicity to image two human breast cancer cell lines T47D and MDA-MB-231 are also evaluated. Additionally, to understand the significance of shape of the nanostructure, the photoluminescence and paramagnetic characteristic of Gd2O3:Eu(3+) nanorods were compared with the spherical nanoparticles of Gd2O3:Eu(3+).

Indexed as

Cell Line, TumorEpithelial CellsEuropiumGadoliniumHumansLuminescent AgentsLuminescent MeasurementsMagnetsNanoparticlesNanotechnologyNanotubesOptical ImagingEuropiumGadoliniumLuminescent Agents

Identifiers

PMID27585638
PMCPMC5009349

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.