Evidence map›Paper›PMID 27584928›Full record

ReviewCurrent opinion in nephrology and hypertension2016

Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases.

Pedro Magalhães, Harald Mischak, Petra Zürbig

Abstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. How Omics Data Can Be Used in Nephrology.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018
    Review
  4. Article
  5. Article
  6. Diagnostic and prognostic tests in systemic lupus erythematosus.Best practice & research. Clinical rheumatology · 2017
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Pedro MagalhãesaMosaiques Diagnostics GmbH bHannover Medical School, Hannover, Germany cInstitute of Cardiovascular and Medical Sciences, University of Glasgow, UK.
Harald Mischak
Petra Zürbig
Medizinische Hochschule Hannover · DEMosaiques Diagnostics and Therapeutics (Germany) · DEUniversity of Glasgow · GB

Funding

Medical Research Council G1000791
6 · The paper itself

Abstract

purpose of reviewUrine is the most useful of body fluids for biomarker research. Therefore, we have focused on urinary proteomics, using capillary electrophoresis coupled to mass spectrometry, to investigate kidney diseases in recent years. RECENT

findingsSeveral urinary proteomics studies for the detection of various kidney diseases have indicated the potential of this approach aimed at diagnostic and prognostic assessment. Urinary protein biomarkers such as collagen fragments, serum albumin, α-1-antitrypsin, and uromodulin can help to explain the processes involved during disease progression. SUMMARY: Urinary proteomics has been used in several studies in order to identify and validate biomarkers associated with different kidney diseases. These biomarkers, with improved sensitivity and specificity when compared with the current gold standards, provide a significant alternative for diagnosis and prognosis, as well as improving clinical decision-making.

Indexed as

BiomarkersDisease ProgressionElectrophoresis, CapillaryHumansMass SpectrometryPolycystic Kidney DiseasesPrognosisProteomicsRenal Insufficiency, ChronicUrinalysisUrinary TractBiomarkers

Identifiers

PMID27584928
PMCPMC6813039
OpenAlexW2515878712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.