Evidence map›Paper›PMID 27584678›Full record

ArticleSpine2017

Pain Recurrence After Discectomy for Symptomatic Lumbar Disc Herniation.

Pradeep Suri, Adam M Pearson, Wenyan Zhao, Jon D Lurie, Emily A Scherer, Tamara S Morgan, James N Weinstein

Abstract read
In one paragraph

Article in Spine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  20. Laser Therapy in Lumbar Disc Surgery - A Narrative Review.Journal of lasers in medical sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pradeep SuriSeattle Epidemiologic Research and Information Center and Division of Rehabilitation Care Services, VA Puget Sound Health Care System, Seattle, WA.
Adam M PearsonDepartment of Orthopaedics, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
Wenyan ZhaoDepartment of Orthopaedics, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
Jon D LurieDepartment of Medicine, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
Emily A SchererDepartment of Medicine, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
Tamara S MorganThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
James N WeinsteinThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine, The Dartmouth-Hitchcock Medical Center, Hanover/Lebanon, NH.
Dartmouth–Hitchcock Medical Center · USDartmouth Institute for Health Policy and Clinical Practice · USUniversity of Washington · US

Funding

LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIALU01AR045444 · NIAMS · DARTMOUTH COLLEGE · PI WEINSTEIN, JAMES N · 1999 to 2013
$20.8M
Prognostic Value of Lumbar Spine MRIP60AR048094 · NIAMS · DARTMOUTH COLLEGE · PI TOSTESON, TOR D. · 2003 to 2007
$6.2M
Outcomes Calculators for Informed Decision Making in Back SurgeryP60AR062799 · NIAMS · DARTMOUTH COLLEGE · PI TOSTESON, TOR D · 2012 to 2016
$6.1M
NIAMS NIH HHS P60 AR048094NIAMS NIH HHS P60 AR062799NIAMS NIH HHS U01 AR045444
6 · The paper itself

Abstract

STUDY

designSecondary analysis of data from a concurrent randomized trial and cohort study.

objectiveThe aim of this study was to determine risks and predictors of recurrent pain following standard open discectomy for subacute/chronic symptomatic lumbar disc herniation (SLDH). SUMMARY OF BACKGROUND DATA: Most previous studies of recurrence after discectomy do not explicitly define pain resolution and recurrence, and do not account for variable durations of time at risk for recurrence.

methodsWe used survival analysis methods to examine predictors of leg pain recurrence. For individuals with initial resolution of leg pain, we defined recurrent leg pain as having leg pain, receiving lumbar epidural steroid injections, or undergoing lumbar surgery subsequent to initial leg pain resolution. We calculated cumulative risks of leg pain recurrence using Kaplan-Meier survival curves, and examined predictors of recurrence using Cox proportional hazards models. We used similar methods to examine LBP recurrence.

resultsOne- and three-year cumulative risks of leg pain recurrence were 20% and 45%, respectively. One- and three- year leg pain recurrence risks were substantially lower in participants with complete initial resolution of leg pain (17% and 41%, respectively) than in those without (27% and 54%, respectively). In multivariate analyses, complete leg pain resolution (adjusted hazard ratio [aHR] 0.69; 95% confidence interval [CI] 0.52-0.90), smoking (aHR 1.68 [95% CI 1.22-2.33]), and depression (aHR 1.74 [95% CI 1.18-2.56]) predicted leg pain recurrence. The 1- and 3-year risk of LBP recurrence was 29% and 65%, respectively. LBP recurrence risk at 3 years was substantially lower in participants with complete initial resolution of LBP than in those without, but not at 1 year.

conclusionRecurrence of leg pain and LBP is common after discectomy for SLDH. Cumulative risks of both leg pain and LBP recurrence were generally lower in participants achieving complete initial resolution of pain post-discectomy. LEVEL OF EVIDENCE: 2.

Indexed as

DiskectomyAdultCohort StudiesFemaleHumansIntervertebral Disc DegenerationIntervertebral Disc DisplacementLumbar VertebraeLumbosacral RegionMaleMiddle AgedPainPain MeasurementRecurrenceTime FactorsTreatment Outcome

Identifiers

PMID27584678
PMCPMC5332353
OpenAlexW2517385036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.