Evidence map›Paper›PMID 27583887›Full record

ReviewMedicine2016

Hypereosinophilic syndrome presenting with multiple organ infiltration and deep venous thrombosis: A case report and literature review.

Su-Jun Gao, Wei Wei, Jiang-Tao Chen, Ye-Hui Tan, Cheng-Bao Yu, Mark Robert Litzow, Qiu-Ju Liu

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Benralizumab for acute thromboembolism in hypereosinophilic syndrome: a case report.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Su-Jun GaoHematology section, Cancer Center, the First Hospital of Jilin University Department of Urology, The First Hospital of Jilin University, Changchun, Jilin, China Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA Second Department of Cardiology, The First Hospital of Qiqihaer Hospital, Qiqihaer, Heilongjiang, China.
Wei Wei
Jiang-Tao Chen
Ye-Hui Tan
Cheng-Bao Yu
Mark Robert Litzow
Qiu-Ju Liu
Jilin University · CNFirst Hospital of Jilin University · CNMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypereosinophilic syndrome (HES) can be fatal, particularly when eosinophils infiltrate vital organs and/or if extensive thrombosis develops. However there are no standard recommendations for the use of anticoagulant therapy of HES in the setting of thrombosis.

methodsWe herein present a case of a 46-year-old female who presented with marked peripheral eosinophilia with symptoms of multi-organ infiltration and extensive deep venous thrombosis (DVT). In this case, evaluation was carried out before the diagnosis was established, and timely standard-dose corticosteroids combined with a new oral anticoagulant (NOAC) therapy were carried out.

resultsThese measures resulted in a rapid response and long-term disease control.

conclusionAlthough there are no data to support which anticoagulant is preferred in this setting, this case indicates that the new oral anticoagulants may play an important role in the treatment of thrombosis in HES.

Indexed as

Anti-Inflammatory AgentsCombined Modality TherapyFactor Xa InhibitorsFemaleHumansHypereosinophilic SyndromeKidneyLiverMiddle AgedPlatelet TransfusionPrednisoloneRivaroxabanThoraxVenous ThrombosisAnti-Inflammatory AgentsFactor Xa InhibitorsPrednisoloneRivaroxaban

Identifiers

PMID27583887
PMCPMC5008571
OpenAlexW2508925266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.