ArticleInvestigative ophthalmology & visual science2016
Peripapillary Pachychoroid in Nonarteritic Anterior Ischemic Optic Neuropathy.
Article in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Optic disc drusen prevalence and visual outcome in a cohort of patients with non-arteritic anterior ischemic optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Baseline retinal nerve fiber layer thickness as a predictive biomarker for endoscopic optic canal decompression in NAION: towards a precision medicine approach.Journal of translational medicine · 2026Article
- Hypercortisolism and ocular microcirculation: exploring retinal and choroidal remodeling in Cushing's disease.International journal of ophthalmology · 2026Article
- Optic disc characteristics evaluated with swept source optical coherence tomography angiography (SS-OCTA) in nonarteritic anterior ischemic optic neuropathy (NAION): a cross-sectional study.BMC ophthalmology · 2025Article
- Subfoveal choroidal thickness increases after excimer laser-assisted penetrating keratoplasty but not after excimer laser-assisted deep anterior lamellar keratoplasty.Scientific reports · 2024Article
- Peripapillary retinal neovascularization and vitreous hemorrhage secondary to peripapillary pachychoroid syndrome.American journal of ophthalmology case reports · 2024Article
- Spaceflight associated neuro-ocular syndrome: connections with terrestrial eye and brain disorders.Frontiers in ophthalmology · 2024Article
- Insights into Ocular Emergencies: case Series on Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Secondary to Acute Angle Closure Glaucoma.International medical case reports journal · 2024Article
- Optic neuropathy in spaceflight-associated neuro-ocular syndrome (SANS).Irish journal of medical science · 2023Article
- Choroidal thickness as a possible predictor of non-response to intravitreal bevacizumab for macular edema after retinal vein occlusion.Scientific reports · 2023Article
- The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.Korean journal of ophthalmology : KJO · 2022Article
- A Potential Role of Acute Choroidal Expansion in Nonarteritic Anterior Ischemic Optic Neuropathy.Investigative ophthalmology & visual science · 2022Article
- Pachychoroid disease spectrum: review article.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- The Role of Optical Coherence Tomography Angiography in Optic Nerve Head Edema: A Narrative Review.Journal of ophthalmology · 2022Review
- Peripapillary Choroidal Vascularity and Visual Correlates in Non-Arteritic Anterior Ischemic Optic Neuropathy Using Swept-Source Optical Coherence Tomography.Frontiers in ophthalmology · 2022Article
- Peripapillary Choroid Thickness as a Predisposing Factor for Nonarteritic Anterior Ischemic Optic Neuropathy: A Semiautomated OCT Study.Translational vision science & technology · 2021Article
- Pachychoroid disease and its association with retinal vein occlusion: a case-control study.Scientific reports · 2021Article
- Alterations in retinal and choroidal thickness following nonarteritic anterior ischemic optic neuropathy.International ophthalmology · 2021Article
- Simultaneous and Bilateral Non-Arteritic Anterior Ischaemic Optic Neuropathy and Acute Angle-Closure.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Bruch's Membrane Opening Minimum Rim Width in the Differential Diagnosis of Optic Neuropathies.Neuro-ophthalmology (Aeolus Press) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeThis study examined the peripapillary choroidal thickness (PCT) in nonarteritic ischemic optic neuropathy (NAION) in comparison to contralateral eyes and normal eyes.
methodsWe used enhanced depth imaging spectral-domain optical coherence tomography to image the optic nerve head of 20 NAION, 10 contralateral eyes, and 102 normal eyes. Following compensation, the scans were manually delineated to identify relevant surfaces including Bruch's membrane opening (BMO), Bruch's membrane, and anterior sclera. The PCT was defined as the measurement between Bruch's membrane and the anterior sclera and was measured at increasing distance from BMO. Models adjusted for age, BMO area, and axial length were used to compare the mean PCT between NAION and normal eyes, and contralateral eyes and normal eyes. Paired t-tests were used to compare the PCT between NAION and contralateral eyes.
resultsThe mean PCT was thicker in NAION and contralateral eyes when compared with normal eyes at all distances from BMO (P < 0.001). The PCT was not significantly thicker in contralateral eyes when compared with affected NAION eyes. Choroidal thickness was thinnest in the inferior quadrant in all eyes regardless of the group.
conclusionsIncreased peripapillary choroidal thickness was noted in both NAION and contralateral eyes. The thicker choroid may be an associated feature or a result of the disorder. Although further longitudinal study is required to determine causation, these findings may suggest that a thickened peripapillary choroid may be a component of the disk-at-risk clinical phenotype.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.