ArticlePloS one2016
Comparing the Incidence of Falls/Fractures in Parkinson's Disease Patients in the US Population.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Innovative technology-based interventions in Parkinson's disease: A systematic review and meta-analysis.Annals of clinical and translational neurology · 2024Pooled it
- Outcomes following spinal instrumented fusions in patients with parkinson's disease: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Prognostic factors for falls in Parkinson's disease: a systematic review.Acta neurologica Belgica · 2024Pooled it
- Interventions for preventing falls in Parkinson's disease.The Cochrane database of systematic reviews · 2022Pooled it
- Cost-effectiveness of the PDSAFE personalised physiotherapy intervention for fall prevention in Parkinson's: an economic evaluation alongside a randomised controlled trial.BMC neurology · 2020Trial
- Early bone health assessment is indicated in Parkinson's: Risk factor analysis in a UK population-based cohort study.Journal of Parkinson's disease · 2026Article
- Fracture incidence and osteoporosis treatment in Parkinson's disease: a population-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Excess risk of fracture in incident Parkinson's disease Medicare beneficiaries.Injury epidemiology · 2026Article
- Exploring the relationship between orthostatic hypotension and gait in people with Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- A systematic review of real-world gait-related digital mobility outcomes in Parkinson's disease.NPJ digital medicine · 2025Article
- Fractures in Parkinson's Disease: Pathophysiology, Prevention, and Orthopedic Outcomes.Cureus · 2025Review
- Evaluation of Mortality in Users of Pimavanserin Compared with Other Atypical Antipsychotics in Patients with Parkinson's Disease Psychosis: An Update.Drug safety · 2025Article
- Assessing and managing bone health and fracture risk in Parkinson's disease: the BONE PARK 2 protocol.Age and ageing · 2025Article
- Feasibility of a Tele-Assisted Home Exercise Program for Balance and Functional Mobility in Persons With Parkinson's Disease (TELEPORT-PD).International journal of telemedicine and applications · 2025Article
- Excessive daytime sleepiness and gait disturbances in patients with Parkinson's disease.Frontiers in aging neuroscience · 2025Article
- Relationship of foot pain with the increased risk of falls in patients with Parkinson's disease.Journal of foot and ankle research · 2024Article
- A Novel Home-Based Telerehabilitation Program Targeting Fall Prevention in Parkinson Disease: A Preliminary Trial.Neurology. Clinical practice · 2024Article
- A machine learning model for prediction of sarcopenia in patients with Parkinson's Disease.PloS one · 2024Article
- Effects of overground gait training assisted by a wearable exoskeleton in patients with Parkinson's disease.Journal of neuroengineering and rehabilitation · 2023Article
- Botulinum Toxin as an Adjunctive Therapy for Immobilization of a Distal Humerus Fracture in Parkinson's Disease-Associated Psychosis: A Case Report.The American journal of case reports · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with Parkinson's disease (PD) may experience falls and/or fractures as a result of disease symptoms. There are limited data available from long-term studies estimating the incidence of falls/fractures in patients with PD. The objective was to compare the incidence rate of falls/fractures in PD patients with non-PD patients in a US population. This was a retrospective study using a US-based claims database (Truven Health MarketScan®) that compared the incidence rate of falls/fractures in PD subjects with non-PD subjects. The study period included the 12 months prior to index date (defined as earliest PD diagnosis [International Classification of Diseases, Ninth Revision, Clinical Modification code 332.0]) and a postindex period to the end of data availability. Fractures were defined by inpatient/outpatient claims as a principal or secondary diagnosis and accompanying procedure codes during the postindex period. Incidence rates and 95% CIs for falls/fractures were calculated as the number of events per 10,000 person-years of follow-up using negative binomial or Poisson regression models. Twenty-eight thousand two hundred and eighty PD subjects were matched to non-PD subjects for the analysis (mean [SD] age, 71.4 [11.8] years; 53% male). A higher incidence rate (adjusted for comorbidities and medications) of all fall/fracture cases and by fall and fracture types was observed for PD subjects versus non-PD subjects; the overall adjusted incidence rate ratio comparing PD to non-PD subjects was 2.05; 95% CI, 1.88-2.24. The incidence rate of falls/fractures was significantly higher in subjects with PD compared with non-PD subjects in a US population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.