ArticlePloS one2016
Preoperative Pain, Symptoms, and Psychological Factors related to Higher Acute Pain Trajectories during Hospitalization for Total Knee Arthroplasty.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Preoperative anxiety assessment in orthopaedic surgery: a systematic review and meta-analysis.International orthopaedics · 2025Pooled it
- "Pain Prehabilitation" in Major Joint Surgery: The Way Forward to Improve Outcomes and Prevent Pain Chronicity.Journal of clinical medicine · 2025Review
- Article
- Factors associated with pain and functional impairment five years after total knee arthroplasty: a prospective observational study.BMC musculoskeletal disorders · 2024Observational
- "I am accustomed to something in my body causing pain": a qualitative study of knee replacement non-improvers' stories of previous painful and stressful experiences.BMC musculoskeletal disorders · 2023Article
- fNIRS brain measures of ongoing nociception during surgical incisions under anesthesia.Neurophotonics · 2022Article
- Article
- High levels of preoperative pain and fatigue are red flags for moderate-severe pain 12 months after total knee arthroplasty-A longitudinal cohort study.Musculoskeletal care · 2021Article
- Article
- AAAPT: Assessment of the Acute Pain Trajectory.Pain medicine (Malden, Mass.) · 2021Article
- Preoperative risk factors associated with chronic pain profiles following total knee arthroplasty.European journal of pain (London, England) · 2021Article
- C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty.International orthopaedics · 2020Article
- Prospective pilot study to identify psychological factors influencing peri-operative pain in total knee arthroplasty (TKA).International orthopaedics · 2020Article
- Psychometric properties of a short version of Lee Fatigue Scale used as a generic PROM in persons with stroke or osteoarthritis: assessment using a Rasch analysis approach.Health and quality of life outcomes · 2020Article
- High pre- and postoperative symptom burden in non-responders to total knee arthroplasty.PloS one · 2020Article
- Prediction of Pain and Opioid Utilization in the Perioperative Period in Patients Undergoing Primary Knee Arthroplasty: Psychophysical and Psychosocial Factors.Pain medicine (Malden, Mass.) · 2019Article
- Should high-power posing be integrated in physical therapy?Journal of physical therapy science · 2017Article
- The relationship between pain with walking and self-rated health 12 months following total knee arthroplasty: a longitudinal study.BMC musculoskeletal disorders · 2017Article
- A comparison of predictors and intensity of acute postsurgical pain in patients undergoing total hip and knee arthroplasty.Journal of pain research · 2017Article
- Post-operative analgesia techniques after total knee arthroplasty: A narrative review.Saudi journal of anaesthesiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesUnrelieved postoperative pain after total knee arthroplasty (TKA) is a significant problem. This longitudinal study investigated how preoperative pain intensity, as well as a comprehensive list of preoperative and perioperative factors, influenced the severity of acute average and worst pain after TKA.
methodsPrior to surgery, 203 patients completed a demographic questionnaire, Lee Fatigue Scale, Fatigue Severity Scale, Hospital Anxiety and Depression Scale, and Brief Illness Perception Questionnaire. Brief Pain Inventory was completed prior to surgery as well as through postoperative days (POD) 0 to 4. Clinical data were extracted from medical records.
resultsSeveral factors were associated with higher levels of preoperative and postoperative pain. Lower preoperative average and worst pain intensity scores were associated with increases in average and worst postoperative pain from POD1 to POD4. A higher number of comorbidities, higher C-reactive protein values, and higher pain interference with function were associated with higher preoperative levels of average pain. Older age, higher fatigue levels, and higher scores on identity and emotional responses to osteoarthritis (OA) were associated with higher preoperative levels of worst pain. Lower perceived consequences of OA were associated with higher pain from POD1 to POD4. Males and patients with lower preoperative scores for average pain had higher worst pain following surgery. DISCUSSION: Patients at higher risk for more severe postoperative pain can be identified through an assessment of pain and other risk factors identified in this study. Future research needs to test the efficacy of interventions that modify patients' perceptions of living with OA and pain intensity before surgery on short and long term postoperative outcomes.
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