ArticleJournal of perinatology : official journal of the California Perinatal Association2016
Excessive gestational weight gain in the first trimester among women with normal glucose tolerance and resulting neonatal adiposity.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neonatal body composition by air displacement plethysmography in healthy term singletons: a systematic review.BMC pediatrics · 2019Pooled it
- Patterns of weight gain during the first half of pregnancy and risk of large newborns in women with insulin-dependent diabetes mellitus.Pregnancy (Hoboken, N.J.) · 2026Article
- The effect of maternal blood glucose control on infant body composition at birth.Early human development · 2025Article
- Methods for modeling gestational weight gain: empirical application using electronic health record data from a safety net population.BMC pregnancy and childbirth · 2025Article
- Probiotic Lactobacillus rhamnosus species: considerations for female reproduction and offspring health.Journal of assisted reproduction and genetics · 2024Review
- An mHealth Intervention to Reduce Gestational Obesity (mami-educ): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2023Article
- Prepare randomized clinical trial: Acceptability, engagement, and lifestyle effects of a weight loss intervention beginning in pre-pregnancy.Obesity science & practice · 2022Article
- Relative Contribution of Gestational Weight Gain, Gestational Diabetes, and Maternal Obesity to Neonatal Fat Mass.Nutrients · 2020Article
- Total and trimester-specific gestational weight gain and infant anthropometric outcomes at birth and 6 months in low-income Hispanic families.Pediatric obesity · 2020Article
- A reduction in sedentary behaviour in obese women during pregnancy reduces neonatal adiposity: the DALI randomised controlled trial.Diabetologia · 2019Article
- Association of cord blood methylation with neonatal leptin: An epigenome wide association study.PloS one · 2019Article
- Cord Blood Metabolites Associated with Newborn Adiposity and Hyperinsulinemia.The Journal of pediatrics · 2018Article
- Article
- Air displacement plethysmography (pea pod) in full-term and pre-term infants: a comprehensive review of accuracy, reproducibility, and practical challenges.Maternal health, neonatology and perinatology · 2018Review
- Maternal and neonatal demographics of macrosomic infants admitted to the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Early Pregnancy Weight Gain Exerts the Strongest Effect on Birth Weight, Posing a Critical Time to Prevent Childhood Obesity.Obesity (Silver Spring, Md.) · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo assess whether weight gain above or below Institute of Medicine (IOM) recommended amounts in an ethnically diverse obstetric population with normal glucose tolerance is associated with differences in neonatal adiposity. STUDY
designIn this prospective cohort study, healthy women with normal glucose tolerance based on the International Association of Diabetes and Pregnancy Study Groups guidelines were enrolled. Gestational weight at multiple time points were collected. Neonatal adiposity was measured by air displacement plethysmography at 24 to 72 h of life. Analyses included Fisher's exact test, analysis of variance and a trajectory analysis using a group-based weight gain trajectory model with a censored normal distribution.
resultsOverweight and obese women were more likely to exceed IOM weight gain guidelines. Regardless, there was no significant difference in %body fat of neonates born to mothers who either met or exceeded gestational weight gain (GWG) guidelines. GWG timing influenced neonatal anthropometrics: women who gained excessively by the first prenatal visit had neonates with significantly higher birth weight (3.91 vs 3.45 kg, P<0.001) and %body fat (13.7 vs 10.9%, P=0.0001) compared with women who had steady and moderate GWG.
conclusionAvoidance of excessive GWG in the first trimester may prevent high amounts of neonatal adiposity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.