Evidence map›Paper›PMID 27583364›Full record

ArticlePloS one2016

Exercise-Induced Hypoxaemia Developed at Sea-Level Influences Responses to Exercise at Moderate Altitude.

Anne-Fleur Gaston, Fabienne Durand, Emma Roca, Grégory Doucende, Ilona Hapkova, Enric Subirats

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Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne-Fleur GastonLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.
Fabienne DurandLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.
Emma RocaLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.
Grégory DoucendeLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.
Ilona HapkovaLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.
Enric SubiratsLaboratoire Européen Performance Santé Altitude-EA4604, Université de Perpignan Via Domitia, Font-Romeu, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the impact of exercise-induced hypoxaemia (EIH) developed at sea-level on exercise responses at moderate acute altitude.

methodsTwenty three subjects divided in three groups of individuals: highly trained with EIH (n = 7); highly trained without EIH (n = 8) and untrained participants (n = 8) performed two maximal incremental tests at sea-level and at 2,150 m. Haemoglobin O2 saturation (SpO2), heart rate, oxygen uptake (VO2) and several ventilatory parameters were measured continuously during the tests.

resultsEIH athletes had a drop in SpO2 from 99 ± 0.8% to 91 ± 1.2% from rest to maximal exercise at sea-level, while the other groups did not exhibit a similar decrease. EIH athletes had a greater decrease in VO2max at altitude compared to non-EIH and untrained groups (-22 ± 7.9%, -16 ± 5.3% and -13 ± 9.4%, respectively). At altitude, non-EIH athletes had a similar drop in SpO2 as EIH athletes (13 ± 0.8%) but greater than untrained participants (6 ± 1.0%). EIH athletes showed greater decrease in maximal heart rate than non-EIH athletes at altitude (8 ± 3.3 bpm and 5 ± 2.9 bpm, respectively).

conclusionEIH athletes demonstrated specific cardiorespiratory response to exercise at moderate altitude compared to non-EIH athletes with a higher decrease in VO2max certainly due to the lower ventilator and HRmax responses. Thus EIH phenomenon developed at sea-level negatively impact performance and cardiorespiratory responses at acute moderate altitude despite no potentiated O2 desaturation.

Indexed as

AltitudeExerciseAdaptation, PhysiologicalAdultHumansHypoxiaMaleOxygen Consumption

Identifiers

PMID27583364
PMCPMC5008680

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.