Evidence map›Paper›PMID 27583345›Full record

ArticleData in brief2016

Monomeric adiponectin increases cell viability in porcine aortic endothelial cells cultured in normal and high glucose conditions: Data on kinases activation.

Elena Grossini, Serena Farruggio, Fatima Qoqaiche, Giulia Raina, Lara Camillo, Lorenzo Sigaudo, David Mary, Nicola Surico, Daniela Surico

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elena GrossiniDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Serena FarruggioDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Fatima QoqaicheDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Giulia RainaDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Lara CamilloDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Lorenzo SigaudoDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
David MaryDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Nicola SuricoDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Daniela SuricoDepartment of Translational Medicine, University East Piedmont "A. Avogadro", Azienda Ospedaliera Universitaria Maggiore della Carità, corso Mazzini 36, Via Solaroli 17, Novara, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITAzienda Ospedaliero Universitaria Maggiore della Carita · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We found that monomeric adiponectin was able to increase cell viability in porcine aortic endothelial cells (PAE) cultured both in normal and high glucose condition. Moreover, in normal glucose condition monomeric adiponectin increased p38MAPK, Akt, ERK1/2 and eNOS phosphorylation in a dose- and time-dependent way. Also in high glucose condition monomeric adiponectin increased eNOS and above kinases phosphorylation with similar patterns but at lower extent. For interpretation of the data presented in this article, please see the research article "Monomeric adiponectin modulates nitric oxide release and calcium movements in porcine aortic endothelial cells in normal/high glucose conditions" (Grossini et al., in press) [1].

Identifiers

PMID27583345
PMCPMC4993859
OpenAlexW2479974722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.